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Amixicile, a novel inhibitor of pyruvate: ferredoxin oxidoreductase, shows efficacy against Clostridium difficile in a mouse infection model.
Warren CA, van Opstal E, Ballard TE, Kennedy A, Wang X, Riggins M, Olekhnovich I, Warthan M, Kolling GL, Guerrant RL, Macdonald TL, Hoffman PS. Warren CA, et al. Among authors: van opstal e. Antimicrob Agents Chemother. 2012 Aug;56(8):4103-11. doi: 10.1128/AAC.00360-12. Epub 2012 May 14. Antimicrob Agents Chemother. 2012. PMID: 22585229 Free PMC article.
Treatment of Clostridium difficile infection using SQ641, a capuramycin analogue, increases post-treatment survival and improves clinical measures of disease in a murine model.
Moore JH 2nd, van Opstal E, Kolling GL, Shin JH, Bogatcheva E, Nikonenko B, Einck L, Phipps AJ, Guerrant RL, Protopopova M, Warren CA. Moore JH 2nd, et al. Among authors: van opstal e. J Antimicrob Chemother. 2016 May;71(5):1300-6. doi: 10.1093/jac/dkv479. Epub 2016 Jan 31. J Antimicrob Chemother. 2016. PMID: 26832756 Free PMC article.
Correction: Defined Nutrient Diets Alter Susceptibility to Clostridium difficile Associated Disease in a Murine Model.
Moore JH, Pinheiro CC, Zaenker EI, Bolick DT, Kolling GL, van Opstal E, Noronha FJ, De Medeiros PH, Rodriguez RS, Lima AA, Guerrant RL, Warren CA. Moore JH, et al. Among authors: van opstal e. PLoS One. 2015 Sep 15;10(9):e0137037. doi: 10.1371/journal.pone.0137037. eCollection 2015. PLoS One. 2015. PMID: 26372249 Free PMC article. No abstract available.
29 results