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Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease.
Fattahi F, Steinbeck JA, Kriks S, Tchieu J, Zimmer B, Kishinevsky S, Zeltner N, Mica Y, El-Nachef W, Zhao H, de Stanchina E, Gershon MD, Grikscheit TC, Chen S, Studer L. Fattahi F, et al. Among authors: grikscheit tc. Nature. 2016 Mar 3;531(7592):105-9. doi: 10.1038/nature16951. Epub 2016 Feb 10. Nature. 2016. PMID: 26863197 Free PMC article.
Human and Murine Tissue-Engineered Colon Exhibit Diverse Neuronal Subtypes and Can Be Populated by Enteric Nervous System Progenitor Cells When Donor Colon Is Aganglionic.
Wieck MM, El-Nachef WN, Hou X, Spurrier RG, Holoyda KA, Schall KA, Mojica SG, Collins MK, Trecartin A, Cheng Z, Frykman PK, Grikscheit TC. Wieck MM, et al. Among authors: grikscheit tc. Tissue Eng Part A. 2016 Jan;22(1-2):53-64. doi: 10.1089/ten.TEA.2015.0120. Epub 2015 Oct 28. Tissue Eng Part A. 2016. PMID: 26414777 Free PMC article.
Neural Crest Cell Implantation Restores Enteric Nervous System Function and Alters the Gastrointestinal Transcriptome in Human Tissue-Engineered Small Intestine.
Schlieve CR, Fowler KL, Thornton M, Huang S, Hajjali I, Hou X, Grubbs B, Spence JR, Grikscheit TC. Schlieve CR, et al. Among authors: grikscheit tc. Stem Cell Reports. 2017 Sep 12;9(3):883-896. doi: 10.1016/j.stemcr.2017.07.017. Epub 2017 Aug 10. Stem Cell Reports. 2017. PMID: 28803915 Free PMC article.
Sprouty2 limits intestinal tuft and goblet cell numbers through GSK3β-mediated restriction of epithelial IL-33.
Schumacher MA, Hsieh JJ, Liu CY, Appel KL, Waddell A, Almohazey D, Katada K, Bernard JK, Bucar EB, Gadeock S, Maselli KM, Washington MK, Grikscheit TC, Warburton D, Rosen MJ, Frey MR. Schumacher MA, et al. Among authors: grikscheit tc. Nat Commun. 2021 Feb 5;12(1):836. doi: 10.1038/s41467-021-21113-7. Nat Commun. 2021. PMID: 33547321 Free PMC article.
Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential.
Worthley DL, Churchill M, Compton JT, Tailor Y, Rao M, Si Y, Levin D, Schwartz MG, Uygur A, Hayakawa Y, Gross S, Renz BW, Setlik W, Martinez AN, Chen X, Nizami S, Lee HG, Kang HP, Caldwell JM, Asfaha S, Westphalen CB, Graham T, Jin G, Nagar K, Wang H, Kheirbek MA, Kolhe A, Carpenter J, Glaire M, Nair A, Renders S, Manieri N, Muthupalani S, Fox JG, Reichert M, Giraud AS, Schwabe RF, Pradere JP, Walton K, Prakash A, Gumucio D, Rustgi AK, Stappenbeck TS, Friedman RA, Gershon MD, Sims P, Grikscheit T, Lee FY, Karsenty G, Mukherjee S, Wang TC. Worthley DL, et al. Among authors: grikscheit t. Cell. 2015 Jan 15;160(1-2):269-84. doi: 10.1016/j.cell.2014.11.042. Cell. 2015. PMID: 25594183 Free PMC article.
NH2-terminal deletion of specific phosphorylation sites on PHOX2B disrupts the formation of enteric neurons in vivo.
Chang DF, Gilliam EA, Nucho LA, Garcia J, Shevchenko Y, Zuber SM, Squillaro AI, Maselli KM, Huang S, Spence JR, Grikscheit TC. Chang DF, et al. Among authors: grikscheit tc. Am J Physiol Gastrointest Liver Physiol. 2021 Jun 1;320(6):G1054-G1066. doi: 10.1152/ajpgi.00073.2021. Epub 2021 Apr 21. Am J Physiol Gastrointest Liver Physiol. 2021. PMID: 33881351 Free article.
90 results