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The N terminus of monoamine transporters is a lever required for the action of amphetamines.
Sucic S, Dallinger S, Zdrazil B, Weissensteiner R, Jørgensen TN, Holy M, Kudlacek O, Seidel S, Cha JH, Gether U, Newman AH, Ecker GF, Freissmuth M, Sitte HH. Sucic S, et al. Among authors: zdrazil b. J Biol Chem. 2010 Apr 2;285(14):10924-38. doi: 10.1074/jbc.M109.083154. Epub 2010 Jan 29. J Biol Chem. 2010. PMID: 20118234 Free PMC article.
Annotating Human P-Glycoprotein Bioassay Data.
Zdrazil B, Pinto M, Vasanthanathan P, Williams AJ, Balderud LZ, Engkvist O, Chichester C, Hersey A, Overington JP, Ecker GF. Zdrazil B, et al. Mol Inform. 2012 Aug;31(8):599-609. doi: 10.1002/minf.201200059. Epub 2012 Aug 7. Mol Inform. 2012. PMID: 23293680 Free PMC article.
Scientific competency questions as the basis for semantically enriched open pharmacological space development.
Azzaoui K, Jacoby E, Senger S, Rodríguez EC, Loza M, Zdrazil B, Pinto M, Williams AJ, de la Torre V, Mestres J, Pastor M, Taboureau O, Rarey M, Chichester C, Pettifer S, Blomberg N, Harland L, Williams-Jones B, Ecker GF. Azzaoui K, et al. Among authors: zdrazil b. Drug Discov Today. 2013 Sep;18(17-18):843-52. doi: 10.1016/j.drudis.2013.05.008. Epub 2013 May 20. Drug Discov Today. 2013. PMID: 23702085 Free article. Review.
Exploiting open data: a new era in pharmacoinformatics.
Goldmann D, Montanari F, Richter L, Zdrazil B, Ecker GF. Goldmann D, et al. Among authors: zdrazil b. Future Med Chem. 2014 Apr;6(5):503-14. doi: 10.4155/fmc.14.13. Future Med Chem. 2014. PMID: 24649954
The application of the open pharmacological concepts triple store (open PHACTS) to support drug discovery research.
Ratnam J, Zdrazil B, Digles D, Cuadrado-Rodriguez E, Neefs JM, Tipney H, Siebes R, Waagmeester A, Bradley G, Chau CH, Richter L, Brea J, Evelo CT, Jacoby E, Senger S, Loza MI, Ecker GF, Chichester C. Ratnam J, et al. Among authors: zdrazil b. PLoS One. 2014 Dec 18;9(12):e115460. doi: 10.1371/journal.pone.0115460. eCollection 2014. PLoS One. 2014. PMID: 25522365 Free PMC article.
49 results