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Allele-Specific Reduction of the Mutant Huntingtin Allele Using Transcription Activator-Like Effectors in Human Huntington's Disease Fibroblasts.
Fink KD, Deng P, Gutierrez J, Anderson JS, Torrest A, Komarla A, Kalomoiris S, Cary W, Anderson JD, Gruenloh W, Duffy A, Tempkin T, Annett G, Wheelock V, Segal DJ, Nolta JA. Fink KD, et al. Among authors: segal dj. Cell Transplant. 2016;25(4):677-86. doi: 10.3727/096368916X690863. Epub 2016 Feb 4. Cell Transplant. 2016. PMID: 26850319 Free PMC article.
Artificial escape from XCI by DNA methylation editing of the CDKL5 gene.
Halmai JANM, Deng P, Gonzalez CE, Coggins NB, Cameron D, Carter JL, Buchanan FKB, Waldo JJ, Lock SR, Anderson JD, O'Geen H, Segal DJ, Nolta J, Fink KD. Halmai JANM, et al. Among authors: segal dj. Nucleic Acids Res. 2020 Mar 18;48(5):2372-2387. doi: 10.1093/nar/gkz1214. Nucleic Acids Res. 2020. PMID: 31925439 Free PMC article.
Translational outcomes in a full gene deletion of ubiquitin protein ligase E3A rat model of Angelman syndrome.
Berg EL, Pride MC, Petkova SP, Lee RD, Copping NA, Shen Y, Adhikari A, Fenton TA, Pedersen LR, Noakes LS, Nieman BJ, Lerch JP, Harris S, Born HA, Peters MM, Deng P, Cameron DL, Fink KD, Beitnere U, O'Geen H, Anderson AE, Dindot SV, Nash KR, Weeber EJ, Wöhr M, Ellegood J, Segal DJ, Silverman JL. Berg EL, et al. Among authors: segal dj. Transl Psychiatry. 2020 Jan 27;10(1):39. doi: 10.1038/s41398-020-0720-2. Transl Psychiatry. 2020. PMID: 32066685 Free PMC article.
An in vivo Cell-Based Delivery Platform for Zinc Finger Artificial Transcription Factors in Pre-clinical Animal Models.
Deng P, Halmai JANM, Beitnere U, Cameron D, Martinez ML, Lee CC, Waldo JJ, Thongphanh K, Adhikari A, Copping N, Petkova SP, Lee RD, Lock S, Palomares M, O'Geen H, Carter J, Gonzalez CE, Buchanan FKB, Anderson JD, Fierro FA, Nolta JA, Tarantal AF, Silverman JL, Segal DJ, Fink KD. Deng P, et al. Among authors: segal dj. Front Mol Neurosci. 2022 Jan 27;14:789913. doi: 10.3389/fnmol.2021.789913. eCollection 2021. Front Mol Neurosci. 2022. PMID: 35153670 Free PMC article.
Quantitative analysis of TALE-DNA interactions suggests polarity effects.
Meckler JF, Bhakta MS, Kim MS, Ovadia R, Habrian CH, Zykovich A, Yu A, Lockwood SH, Morbitzer R, Elsäesser J, Lahaye T, Segal DJ, Baldwin EP. Meckler JF, et al. Among authors: segal dj. Nucleic Acids Res. 2013 Apr;41(7):4118-28. doi: 10.1093/nar/gkt085. Epub 2013 Feb 13. Nucleic Acids Res. 2013. PMID: 23408851 Free PMC article.
119 results