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Affinity-based methods in drug-target discovery.
Rylova G, Ozdian T, Varanasi L, Soural M, Hlavac J, Holub D, Dzubak P, Hajduch M. Rylova G, et al. Among authors: varanasi l. Curr Drug Targets. 2015;16(1):60-76. doi: 10.2174/1389450115666141120110323. Curr Drug Targets. 2015. PMID: 25410410
Proteomic profiling reveals DNA damage, nucleolar and ribosomal stress are the main responses to oxaliplatin treatment in cancer cells.
Ozdian T, Holub D, Maceckova Z, Varanasi L, Rylova G, Rehulka J, Vaclavkova J, Slavik H, Moudry P, Znojek P, Stankova J, de Sanctis JB, Hajduch M, Dzubak P. Ozdian T, et al. Among authors: varanasi l. J Proteomics. 2017 Jun 6;162:73-85. doi: 10.1016/j.jprot.2017.05.005. Epub 2017 May 3. J Proteomics. 2017. PMID: 28478306
Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice.
Wali JA, Galic S, Tan CY, Gurzov EN, Frazier AE, Connor T, Ge J, Pappas EG, Stroud D, Varanasi LC, Selck C, Ryan MT, Thorburn DR, Kemp BE, Krishnamurthy B, Kay TW, McGee SL, Thomas HE. Wali JA, et al. Among authors: varanasi lc. Cell Death Differ. 2018 Jan;25(1):217-225. doi: 10.1038/cdd.2017.168. Epub 2017 Oct 20. Cell Death Differ. 2018. PMID: 29053141 Free PMC article.
A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis.
Subramanian M, Francis P, Bilke S, Li XL, Hara T, Lu X, Jones MF, Walker RL, Zhu Y, Pineda M, Lee C, Varanasi L, Yang Y, Martinez LA, Luo J, Ambs S, Sharma S, Wakefield LM, Meltzer PS, Lal A. Subramanian M, et al. Among authors: varanasi l. Oncogene. 2015 Feb 26;34(9):1094-104. doi: 10.1038/onc.2014.46. Epub 2014 Mar 24. Oncogene. 2015. PMID: 24662829 Free PMC article.
15 results