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Chemical Polysialylation and In Vivo Tetramerization Improve Pharmacokinetic Characteristics of Recombinant Human Butyrylcholinesterase-Based Bioscavengers.
Terekhov SS, Smirnov IV, Shamborant OG, Bobik TV, Ilyushin DG, Murashev AN, Dyachenko IA, Palikov VA, Knorre VD, Belogurov AA, Ponomarenko NA, Kuzina ES, Genkin DD, Masson P, Gabibov AG. Terekhov SS, et al. Among authors: masson p. Acta Naturae. 2015 Oct-Dec;7(4):136-41. Acta Naturae. 2015. PMID: 26798501 Free PMC article.
Reactibodies generated by kinetic selection couple chemical reactivity with favorable protein dynamics.
Smirnov I, Carletti E, Kurkova I, Nachon F, Nicolet Y, Mitkevich VA, Débat H, Avalle B, Belogurov AA Jr, Kuznetsov N, Reshetnyak A, Masson P, Tonevitsky AG, Ponomarenko N, Makarov AA, Friboulet A, Tramontano A, Gabibov A. Smirnov I, et al. Among authors: masson p. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15954-9. doi: 10.1073/pnas.1108460108. Epub 2011 Sep 6. Proc Natl Acad Sci U S A. 2011. PMID: 21896761 Free PMC article.
Chemical polysialylation of human recombinant butyrylcholinesterase delivers a long-acting bioscavenger for nerve agents in vivo.
Ilyushin DG, Smirnov IV, Belogurov AA Jr, Dyachenko IA, Zharmukhamedova TIu, Novozhilova TI, Bychikhin EA, Serebryakova MV, Kharybin ON, Murashev AN, Anikienko KA, Nikolaev EN, Ponomarenko NA, Genkin DD, Blackburn GM, Masson P, Gabibov AG. Ilyushin DG, et al. Among authors: masson p. Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1243-8. doi: 10.1073/pnas.1211118110. Epub 2013 Jan 7. Proc Natl Acad Sci U S A. 2013. PMID: 23297221 Free PMC article.
A novel expression cassette delivers efficient production of exclusively tetrameric human butyrylcholinesterase with improved pharmacokinetics for protection against organophosphate poisoning.
Terekhov S, Smirnov I, Bobik T, Shamborant O, Zenkova M, Chernolovskaya E, Gladkikh D, Murashev A, Dyachenko I, Palikov V, Palikova Y, Knorre V, Belogurov A Jr, Ponomarenko N, Blackburn GM, Masson P, Gabibov A. Terekhov S, et al. Among authors: masson p. Biochimie. 2015 Nov;118:51-9. doi: 10.1016/j.biochi.2015.07.028. Epub 2015 Aug 1. Biochimie. 2015. PMID: 26239905
Microfluidic droplet platform for ultrahigh-throughput single-cell screening of biodiversity.
Terekhov SS, Smirnov IV, Stepanova AV, Bobik TV, Mokrushina YA, Ponomarenko NA, Belogurov AA Jr, Rubtsova MP, Kartseva OV, Gomzikova MO, Moskovtsev AA, Bukatin AS, Dubina MV, Kostryukova ES, Babenko VV, Vakhitova MT, Manolov AI, Malakhova MV, Kornienko MA, Tyakht AV, Vanyushkina AA, Ilina EN, Masson P, Gabibov AG, Altman S. Terekhov SS, et al. Among authors: masson p. Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2550-2555. doi: 10.1073/pnas.1621226114. Epub 2017 Feb 15. Proc Natl Acad Sci U S A. 2017. PMID: 28202731 Free PMC article.
857 results