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Cyclin E1 and RTK/RAS signaling drive CDK inhibitor resistance via activation of E2F and ETS.
Taylor-Harding B, Aspuria PJ, Agadjanian H, Cheon DJ, Mizuno T, Greenberg D, Allen JR, Spurka L, Funari V, Spiteri E, Wang Q, Orsulic S, Walsh C, Karlan BY, Wiedemeyer WR. Taylor-Harding B, et al. Among authors: agadjanian h. Oncotarget. 2015 Jan 20;6(2):696-714. doi: 10.18632/oncotarget.2673. Oncotarget. 2015. PMID: 25557169 Free PMC article.
Resistance to receptor-blocking therapies primes tumors as targets for HER3-homing nanobiologics.
Sims JD, Taguiam JM, Alonso-Valenteen F, Markman J, Agadjanian H, Chu D, Lubow J, Abrol R, Srinivas D, Jain A, Han B, Qu Y, Mirzadehgan P, Hwang JY, Rentsendorj A, Chung A, Lester J, Karlan BY, Gray HB, Gross Z, Giuliano A, Cui X, Medina-Kauwe LK. Sims JD, et al. Among authors: agadjanian h. J Control Release. 2018 Feb 10;271:127-138. doi: 10.1016/j.jconrel.2017.12.024. Epub 2017 Dec 27. J Control Release. 2018. PMID: 29288681 Free PMC article.
A mechanistic study of tumor-targeted corrole toxicity.
Hwang JY, Lubow J, Chu D, Ma J, Agadjanian H, Sims J, Gray HB, Gross Z, Farkas DL, Medina-Kauwe LK. Hwang JY, et al. Among authors: agadjanian h. Mol Pharm. 2011 Dec 5;8(6):2233-43. doi: 10.1021/mp200094w. Epub 2011 Oct 25. Mol Pharm. 2011. PMID: 21981771 Free PMC article.
Tumor detection and elimination by a targeted gallium corrole.
Agadjanian H, Ma J, Rentsendorj A, Valluripalli V, Hwang JY, Mahammed A, Farkas DL, Gray HB, Gross Z, Medina-Kauwe LK. Agadjanian H, et al. Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6105-10. doi: 10.1073/pnas.0901531106. Epub 2009 Apr 2. Proc Natl Acad Sci U S A. 2009. PMID: 19342490 Free PMC article.
Chemotherapy targeting by DNA capture in viral protein particles.
Agadjanian H, Chu D, Hwang JY, Wachsmann-Hogiu S, Rentsendorj A, Song L, Valluripalli V, Lubow J, Ma J, Sharifi B, Farkas DL, Medina-Kauwe LK. Agadjanian H, et al. Nanomedicine (Lond). 2012 Mar;7(3):335-52. doi: 10.2217/nnm.11.104. Nanomedicine (Lond). 2012. PMID: 22385197 Free PMC article.
17 results