Pos KM - Search Results

1

Molecular basis of polyspecificity of the Small Multidrug Resistance Efflux Pump AbeS from Acinetobacter baumannii.

Lytvynenko I, Brill S, Oswald C, Pos KM. Lytvynenko I, et al. Among authors: pos km. J Mol Biol. 2016 Feb 13;428(3):644-657. doi: 10.1016/j.jmb.2015.12.006. Epub 2015 Dec 18. J Mol Biol. 2016. PMID: 26707198

2

Drug transport mechanism of the AcrB efflux pump.

Pos KM. Pos KM. Biochim Biophys Acta. 2009 May;1794(5):782-93. doi: 10.1016/j.bbapap.2008.12.015. Epub 2009 Jan 3. Biochim Biophys Acta. 2009. PMID: 19166984 Review.

3

Trinity revealed: Stoichiometric complex assembly of a bacterial multidrug efflux pump.

Pos KM. Pos KM. Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):6893-4. doi: 10.1073/pnas.0902837106. Epub 2009 Apr 22. Proc Natl Acad Sci U S A. 2009. PMID: 19416927 Free PMC article. No abstract available.

4

Drug resistance: a periplasmic ménage à trois.

Oswald C, Pos KM. Oswald C, et al. Among authors: pos km. Chem Biol. 2011 Apr 22;18(4):405-7. doi: 10.1016/j.chembiol.2011.04.004. Chem Biol. 2011. PMID: 21513873

5

The outer membrane TolC-like channel HgdD is part of tripartite resistance-nodulation-cell division (RND) efflux systems conferring multiple-drug resistance in the Cyanobacterium Anabaena sp. PCC7120.

Hahn A, Stevanovic M, Mirus O, Lytvynenko I, Pos KM, Schleiff E. Hahn A, et al. Among authors: pos km. J Biol Chem. 2013 Oct 25;288(43):31192-205. doi: 10.1074/jbc.M113.495598. Epub 2013 Sep 6. J Biol Chem. 2013. PMID: 24014018 Free PMC article.

6

Detecting substrates bound to the secondary multidrug efflux pump EmrE by DNP-enhanced solid-state NMR.

Ong YS, Lakatos A, Becker-Baldus J, Pos KM, Glaubitz C. Ong YS, et al. Among authors: pos km. J Am Chem Soc. 2013 Oct 23;135(42):15754-62. doi: 10.1021/ja402605s. Epub 2013 Oct 11. J Am Chem Soc. 2013. PMID: 24047229

7

Switch-loop flexibility affects transport of large drugs by the promiscuous AcrB multidrug efflux transporter.

Cha HJ, Müller RT, Pos KM. Cha HJ, et al. Among authors: pos km. Antimicrob Agents Chemother. 2014 Aug;58(8):4767-72. doi: 10.1128/AAC.02733-13. Epub 2014 Jun 9. Antimicrob Agents Chemother. 2014. PMID: 24914123 Free PMC article.

8

Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB.

Eicher T, Seeger MA, Anselmi C, Zhou W, Brandstätter L, Verrey F, Diederichs K, Faraldo-Gómez JD, Pos KM. Eicher T, et al. Among authors: pos km. Elife. 2014 Sep 19;3:e03145. doi: 10.7554/eLife.03145. Elife. 2014. PMID: 25248080 Free PMC article.

9

Structure, mechanism and cooperation of bacterial multidrug transporters.

Du D, van Veen HW, Murakami S, Pos KM, Luisi BF. Du D, et al. Among authors: pos km. Curr Opin Struct Biol. 2015 Aug;33:76-91. doi: 10.1016/j.sbi.2015.07.015. Epub 2015 Aug 15. Curr Opin Struct Biol. 2015. PMID: 26282926 Free article. Review.

10

Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives.

Sjuts H, Vargiu AV, Kwasny SM, Nguyen ST, Kim HS, Ding X, Ornik AR, Ruggerone P, Bowlin TL, Nikaido H, Pos KM, Opperman TJ. Sjuts H, et al. Among authors: pos km. Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3509-14. doi: 10.1073/pnas.1602472113. Epub 2016 Mar 14. Proc Natl Acad Sci U S A. 2016. PMID: 26976576 Free PMC article.

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