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Plasmodium falciparum dihydroartemisinin-piperaquine failures in Cambodia are associated with mutant K13 parasites presenting high survival rates in novel piperaquine in vitro assays: retrospective and prospective investigations.
Duru V, Khim N, Leang R, Kim S, Domergue A, Kloeung N, Ke S, Chy S, Eam R, Khean C, Loch K, Ken M, Lek D, Beghain J, Ariey F, Guerin PJ, Huy R, Mercereau-Puijalon O, Witkowski B, Menard D. Duru V, et al. Among authors: ke s. BMC Med. 2015 Dec 22;13:305. doi: 10.1186/s12916-015-0539-5. BMC Med. 2015. PMID: 26695060 Free PMC article.
Reduced artemisinin susceptibility of Plasmodium falciparum ring stages in western Cambodia.
Witkowski B, Khim N, Chim P, Kim S, Ke S, Kloeung N, Chy S, Duong S, Leang R, Ringwald P, Dondorp AM, Tripura R, Benoit-Vical F, Berry A, Gorgette O, Ariey F, Barale JC, Mercereau-Puijalon O, Menard D. Witkowski B, et al. Among authors: ke s. Antimicrob Agents Chemother. 2013 Feb;57(2):914-23. doi: 10.1128/AAC.01868-12. Epub 2012 Dec 3. Antimicrob Agents Chemother. 2013. PMID: 23208708 Free PMC article.
A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype-genotype association study.
Witkowski B, Duru V, Khim N, Ross LS, Saintpierre B, Beghain J, Chy S, Kim S, Ke S, Kloeung N, Eam R, Khean C, Ken M, Loch K, Bouillon A, Domergue A, Ma L, Bouchier C, Leang R, Huy R, Nuel G, Barale JC, Legrand E, Ringwald P, Fidock DA, Mercereau-Puijalon O, Ariey F, Ménard D. Witkowski B, et al. Among authors: ke s. Lancet Infect Dis. 2017 Feb;17(2):174-183. doi: 10.1016/S1473-3099(16)30415-7. Epub 2016 Nov 3. Lancet Infect Dis. 2017. PMID: 27818097 Free PMC article.
In vitro activity of ferroquine against artemisinin-based combination therapy (ACT)-resistant Plasmodium falciparum isolates from Cambodia.
Mairet-Khedim M, Nardella F, Khim N, Kim S, Kloeung N, Ke S, Kauy C, Eam R, Khean C, Pellet A, Leboulleux D, Leang R, Ringwald P, Barale JC, Leroy D, Menard D, Witkowski B. Mairet-Khedim M, et al. Among authors: ke s. J Antimicrob Chemother. 2019 Nov 1;74(11):3240-3244. doi: 10.1093/jac/dkz340. J Antimicrob Chemother. 2019. PMID: 31518407
Prevalence and characterization of piperaquine, mefloquine and artemisinin derivatives triple-resistant Plasmodium falciparum in Cambodia.
Mairet-Khedim M, Roesch C, Khim N, Srun S, Bouillon A, Kim S, Ke S, Kauy C, Kloeung N, Eam R, Khean C, Kul C, Chy S, Leang R, Ringwald P, Barale JC, Witkowski B. Mairet-Khedim M, et al. Among authors: ke s. J Antimicrob Chemother. 2023 Feb 1;78(2):411-417. doi: 10.1093/jac/dkac403. J Antimicrob Chemother. 2023. PMID: 36508338 Free PMC article.
1,045 results