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Discovery of Potent and Selective Covalent Inhibitors of HER2WT and HER2YVMA.
Hicken EJ, Brown K, Dwulet NC, Gaudino JJ, Hansen EP, Hartley DP, Kowalski JP, Laird ER, Lazzara NC, Li B, Mou TC, Mutryn MF, Oko L, Pajk S, Pipal RW, Rosen RZ, Shelp R, Singh A, Wang J, Wise CE, Wong C, Wong JY. Hicken EJ, et al. Among authors: mou tc. J Med Chem. 2024 May 31. doi: 10.1021/acs.jmedchem.4c00978. Online ahead of print. J Med Chem. 2024. PMID: 38820338
A next-generation BRAF inhibitor overcomes resistance to BRAF inhibition in patients with BRAF-mutant cancers using pharmacokinetics-informed dose escalation.
Yaeger R, McKean MA, Haq R, Beck JT, Taylor MH, Cohen JE, Bowles DW, Gadgeel SM, Mihalcioiu C, Papadopoulos KP, Diamond EL, Sturtz KB, Feng G, Drescher SK, Reddy MB, Sengupta B, Maity AK, Brown SA, Singh A, Brown EN, Baer BR, Wong J, Mou TC, Wu WI, Kahn DR, Gadal S, Rosen N, Gaudino JJ, Lee PA, Hartley DP, Rothenberg SM. Yaeger R, et al. Among authors: mou tc. Cancer Discov. 2024 Apr 30. doi: 10.1158/2159-8290.CD-24-0024. Online ahead of print. Cancer Discov. 2024. PMID: 38691346
Experimenters' sex modulates mouse behaviors and neural responses to ketamine via corticotropin releasing factor.
Georgiou P, Zanos P, Mou TM, An X, Gerhard DM, Dryanovski DI, Potter LE, Highland JN, Jenne CE, Stewart BW, Pultorak KJ, Yuan P, Powels CF, Lovett J, Pereira EFR, Clark SM, Tonelli LH, Moaddel R, Zarate CA Jr, Duman RS, Thompson SM, Gould TD. Georgiou P, et al. Nat Neurosci. 2022 Sep;25(9):1191-1200. doi: 10.1038/s41593-022-01146-x. Epub 2022 Aug 30. Nat Neurosci. 2022. PMID: 36042309 Free PMC article.
50 results