Zanger UM - Search Results

1

Gene copy number variation analysis reveals dosage-insensitive expression of CYP2E1.

Tremmel R, Klein K, Winter S, Schaeffeler E, Zanger UM. Tremmel R, et al. Among authors: zanger um. Pharmacogenomics J. 2016 Nov;16(6):551-558. doi: 10.1038/tpj.2015.69. Epub 2015 Oct 27. Pharmacogenomics J. 2016. PMID: 26503817

2

Pharmacogenomics of human liver cytochrome P450 oxidoreductase: multifactorial analysis and impact on microsomal drug oxidation.

Gomes AM, Winter S, Klein K, Turpeinen M, Schaeffeler E, Schwab M, Zanger UM. Gomes AM, et al. Among authors: zanger um. Pharmacogenomics. 2009 Apr;10(4):579-99. doi: 10.2217/pgs.09.7. Pharmacogenomics. 2009. PMID: 19374516 Free article.

3

ABCC11/MRP8 polymorphisms affect 5-fluorouracil-induced severe toxicity and hepatic expression.

Magdy T, Arlanov R, Winter S, Lang T, Klein K, Toyoda Y, Ishikawa T, Schwab M, Zanger UM. Magdy T, et al. Among authors: zanger um. Pharmacogenomics. 2013 Sep;14(12):1433-48. doi: 10.2217/pgs.13.139. Pharmacogenomics. 2013. PMID: 24024896

4

Methyleugenol DNA adducts in human liver are associated with SULT1A1 copy number variations and expression levels.

Tremmel R, Herrmann K, Engst W, Meinl W, Klein K, Glatt H, Zanger UM. Tremmel R, et al. Among authors: zanger um. Arch Toxicol. 2017 Oct;91(10):3329-3339. doi: 10.1007/s00204-017-1955-4. Epub 2017 Mar 22. Arch Toxicol. 2017. PMID: 28326452

5

Copy number variation profiling in pharmacogenes using panel-based exome resequencing and correlation to human liver expression.

Tremmel R, Klein K, Battke F, Fehr S, Winter S, Scheurenbrand T, Schaeffeler E, Biskup S, Schwab M, Zanger UM. Tremmel R, et al. Among authors: zanger um. Hum Genet. 2020 Feb;139(2):137-149. doi: 10.1007/s00439-019-02093-7. Epub 2019 Nov 30. Hum Genet. 2020. PMID: 31786673

6

Variability in human hepatic MRP4 expression: influence of cholestasis and genotype.

Gradhand U, Lang T, Schaeffeler E, Glaeser H, Tegude H, Klein K, Fritz P, Jedlitschky G, Kroemer HK, Bachmakov I, Anwald B, Kerb R, Zanger UM, Eichelbaum M, Schwab M, Fromm MF. Gradhand U, et al. Among authors: zanger um. Pharmacogenomics J. 2008 Feb;8(1):42-52. doi: 10.1038/sj.tpj.6500451. Epub 2007 Apr 3. Pharmacogenomics J. 2008. PMID: 17404579

7

Genomics of ADME gene expression: mapping expression quantitative trait loci relevant for absorption, distribution, metabolism and excretion of drugs in human liver.

Schröder A, Klein K, Winter S, Schwab M, Bonin M, Zell A, Zanger UM. Schröder A, et al. Among authors: zanger um. Pharmacogenomics J. 2013 Feb;13(1):12-20. doi: 10.1038/tpj.2011.44. Epub 2011 Oct 18. Pharmacogenomics J. 2013. PMID: 22006096 Free PMC article.

8

Variability in hepatic expression of organic anion transporter 7/SLC22A9, a novel pravastatin uptake transporter: impact of genetic and regulatory factors.

Emami Riedmaier A, Burk O, van Eijck BA, Schaeffeler E, Klein K, Fehr S, Biskup S, Müller S, Winter S, Zanger UM, Schwab M, Nies AT. Emami Riedmaier A, et al. Among authors: zanger um. Pharmacogenomics J. 2016 Aug;16(4):341-51. doi: 10.1038/tpj.2015.55. Epub 2015 Aug 4. Pharmacogenomics J. 2016. PMID: 26239079

9

CYP2D6 genotyping strategy based on gene copy number determination by TaqMan real-time PCR.

Schaeffeler E, Schwab M, Eichelbaum M, Zanger UM. Schaeffeler E, et al. Among authors: zanger um. Hum Mutat. 2003 Dec;22(6):476-85. doi: 10.1002/humu.10280. Hum Mutat. 2003. PMID: 14635107

10

Three novel thiopurine S-methyltransferase allelic variants (TPMT*20, *21, *22) - association with decreased enzyme function.

Schaeffeler E, Eichelbaum M, Reinisch W, Zanger UM, Schwab M. Schaeffeler E, et al. Among authors: zanger um. Hum Mutat. 2006 Sep;27(9):976. doi: 10.1002/humu.9450. Hum Mutat. 2006. PMID: 16917910

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