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A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease.
Nat Chem Biol. 2015 Dec;11(12):973-980. doi: 10.1038/nchembio.1952. Epub 2015 Oct 26.
Nat Chem Biol. 2015.
PMID: 26502155
Free PMC article.
Discovery of potent, orally bioavailable, small-molecule inhibitors of WNT signaling from a cell-based pathway screen.
Mallinger A, Crumpler S, Pichowicz M, Waalboer D, Stubbs M, Adeniji-Popoola O, Wood B, Smith E, Thai C, Henley AT, Georgi K, Court W, Hobbs S, Box G, Ortiz-Ruiz MJ, Valenti M, De Haven Brandon A, TePoele R, Leuthner B, Workman P, Aherne W, Poeschke O, Dale T, Wienke D, Esdar C, Rohdich F, Raynaud F, Clarke PA, Eccles SA, Stieber F, Schiemann K, Blagg J.
Mallinger A, et al. Among authors: waalboer d.
J Med Chem. 2015 Feb 26;58(4):1717-35. doi: 10.1021/jm501436m. Epub 2015 Feb 13.
J Med Chem. 2015.
PMID: 25680029
Free PMC article.
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A Novel Platinum(II)-Based Bifunctional ADC Linker Benchmarked Using 89Zr-Desferal and Auristatin F-Conjugated Trastuzumab.
Sijbrandi NJ, Merkul E, Muns JA, Waalboer DC, Adamzek K, Bolijn M, Montserrat V, Somsen GW, Haselberg R, Steverink PJ, Houthoff HJ, van Dongen GA.
Sijbrandi NJ, et al. Among authors: waalboer dc.
Cancer Res. 2017 Jan 15;77(2):257-267. doi: 10.1158/0008-5472.CAN-16-1900. Epub 2016 Nov 21.
Cancer Res. 2017.
PMID: 27872093
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Platinum(II) as bifunctional linker in antibody-drug conjugate formation: coupling of a 4-nitrobenzo-2-oxa-1,3-diazole fluorophore to trastuzumab as a model.
Waalboer DC, Muns JA, Sijbrandi NJ, Schasfoort RB, Haselberg R, Somsen GW, Houthoff HJ, van Dongen GA.
Waalboer DC, et al.
ChemMedChem. 2015 May;10(5):797-803. doi: 10.1002/cmdc.201402496. Epub 2015 Mar 25.
ChemMedChem. 2015.
PMID: 25809281
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Total synthesis and antibiotic activity of dehydrohomoplatencin.
Waalboer DC, Leenders SH, Schülin-Casonato T, van Delft FL, Rutjes FP.
Waalboer DC, et al.
Chemistry. 2010 Oct 4;16(37):11233-6. doi: 10.1002/chem.201001744.
Chemistry. 2010.
PMID: 20715217
No abstract available.
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Total synthesis and absolute stereochemistry of integric acid.
Waalboer DC, van Kalkeren HA, Schaapman MC, van Delft FL, Rutjes FP.
Waalboer DC, et al.
J Org Chem. 2009 Nov 20;74(22):8878-81. doi: 10.1021/jo901845r.
J Org Chem. 2009.
PMID: 19860426
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High-pressure entry into platencin.
Waalboer DC, Schaapman MC, van Delft FL, Rutjes FP.
Waalboer DC, et al.
Angew Chem Int Ed Engl. 2008;47(35):6576-8. doi: 10.1002/anie.200802912.
Angew Chem Int Ed Engl. 2008.
PMID: 18666193
No abstract available.
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