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Development of intravenously administered synthetic RNA virus immunotherapy for the treatment of cancer.
Kennedy EM, Denslow A, Hewett J, Kong L, De Almeida A, Bryant JD, Lee JS, Jacques J, Feau S, Hayes M, McMichael EL, Wambua D, Farkaly T, Rahmeh AA, Herschelman L, Douglas D, Spinale J, Adhikari S, Deterling J, Scott M, Haines BB, Finer MH, Ashburn TT, Quéva C, Lerner L. Kennedy EM, et al. Among authors: farkaly t. Nat Commun. 2022 Oct 7;13(1):5907. doi: 10.1038/s41467-022-33599-w. Nat Commun. 2022. PMID: 36207308 Free PMC article.
ONCR-177, an Oncolytic HSV-1 Designed to Potently Activate Systemic Antitumor Immunity.
Haines BB, Denslow A, Grzesik P, Lee JS, Farkaly T, Hewett J, Wambua D, Kong L, Behera P, Jacques J, Goshert C, Ball M, Colthart A, Finer MH, Hayes MW, Feau S, Kennedy EM, Lerner L, Quéva C. Haines BB, et al. Among authors: farkaly t. Cancer Immunol Res. 2021 Mar;9(3):291-308. doi: 10.1158/2326-6066.CIR-20-0609. Epub 2020 Dec 22. Cancer Immunol Res. 2021. PMID: 33355229
Design of an Interferon-Resistant Oncolytic HSV-1 Incorporating Redundant Safety Modalities for Improved Tolerability.
Kennedy EM, Farkaly T, Grzesik P, Lee J, Denslow A, Hewett J, Bryant J, Behara P, Goshert C, Wambua D, De Almeida A, Jacques J, Deavall D, Rottman JB, Glorioso JC, Finer MH, Haines BB, Quéva C, Lerner L. Kennedy EM, et al. Among authors: farkaly t. Mol Ther Oncolytics. 2020 Aug 8;18:476-490. doi: 10.1016/j.omto.2020.08.004. eCollection 2020 Sep 25. Mol Ther Oncolytics. 2020. PMID: 32953982 Free PMC article.