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The Lectin-like Domain of TNF Increases ENaC Open Probability through a Novel Site at the Interface between the Second Transmembrane and C-terminal Domains of the α-Subunit.
Lucas R, Yue Q, Alli A, Duke BJ, Al-Khalili O, Thai TL, Hamacher J, Sridhar S, Lebedyeva I, Su H, Tzotzos S, Fischer B, Gameiro AF, Loose M, Chakraborty T, Shabbir W, Aufy M, Lemmens-Gruber R, Eaton DC, Czikora I. Lucas R, et al. Among authors: thai tl. J Biol Chem. 2016 Nov 4;291(45):23440-23451. doi: 10.1074/jbc.M116.718163. Epub 2016 Sep 19. J Biol Chem. 2016. PMID: 27645999 Free PMC article.
ENaC activity is regulated by calpain-2 proteolysis of MARCKS proteins.
Montgomery DS, Yu L, Ghazi ZM, Thai TL, Al-Khalili O, Ma HP, Eaton DC, Alli AA. Montgomery DS, et al. Among authors: thai tl. Am J Physiol Cell Physiol. 2017 Jul 1;313(1):C42-C53. doi: 10.1152/ajpcell.00244.2016. Epub 2017 May 3. Am J Physiol Cell Physiol. 2017. PMID: 28468944 Free PMC article.
Alveolar nonselective channels are ASIC1a/α-ENaC channels and contribute to AFC.
Trac PT, Thai TL, Linck V, Zou L, Greenlee M, Yue Q, Al-Khalili O, Alli AA, Eaton AF, Eaton DC. Trac PT, et al. Among authors: thai tl. Am J Physiol Lung Cell Mol Physiol. 2017 Jun 1;312(6):L797-L811. doi: 10.1152/ajplung.00379.2016. Epub 2017 Mar 10. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 28283476 Free PMC article.
33 results