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ATF3 Is a Key Regulator of Macrophage IFN Responses.
Labzin LI, Schmidt SV, Masters SL, Beyer M, Krebs W, Klee K, Stahl R, Lütjohann D, Schultze JL, Latz E, De Nardo D. Labzin LI, et al. Among authors: masters sl. J Immunol. 2015 Nov 1;195(9):4446-55. doi: 10.4049/jimmunol.1500204. Epub 2015 Sep 28. J Immunol. 2015. PMID: 26416280
TLR regulation of SPSB1 controls inducible nitric oxide synthase induction.
Lewis RS, Kolesnik TB, Kuang Z, D'Cruz AA, Blewitt ME, Masters SL, Low A, Willson T, Norton RS, Nicholson SE. Lewis RS, et al. Among authors: masters sl. J Immunol. 2011 Oct 1;187(7):3798-805. doi: 10.4049/jimmunol.1002993. Epub 2011 Aug 29. J Immunol. 2011. PMID: 21876038
Innate immunity.
Masters SL, De Nardo D. Masters SL, et al. Curr Opin Immunol. 2014 Feb;26:v-vi. doi: 10.1016/j.coi.2013.12.006. Epub 2014 Feb 1. Curr Opin Immunol. 2014. PMID: 24495628 No abstract available.
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Coll RC, Robertson AA, Chae JJ, Higgins SC, Muñoz-Planillo R, Inserra MC, Vetter I, Dungan LS, Monks BG, Stutz A, Croker DE, Butler MS, Haneklaus M, Sutton CE, Núñez G, Latz E, Kastner DL, Mills KH, Masters SL, Schroder K, Cooper MA, O'Neill LA. Coll RC, et al. Among authors: masters sl. Nat Med. 2015 Mar;21(3):248-55. doi: 10.1038/nm.3806. Epub 2015 Feb 16. Nat Med. 2015. PMID: 25686105 Free PMC article.
Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β.
Kim ML, Chae JJ, Park YH, De Nardo D, Stirzaker RA, Ko HJ, Tye H, Cengia L, DiRago L, Metcalf D, Roberts AW, Kastner DL, Lew AM, Lyras D, Kile BT, Croker BA, Masters SL. Kim ML, et al. Among authors: masters sl. J Exp Med. 2015 Jun 1;212(6):927-38. doi: 10.1084/jem.20142384. Epub 2015 May 25. J Exp Med. 2015. PMID: 26008898 Free PMC article.
Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.
Sester DP, Sagulenko V, Thygesen SJ, Cridland JA, Loi YS, Cridland SO, Masters SL, Genske U, Hornung V, Andoniou CE, Sweet MJ, Degli-Esposti MA, Schroder K, Stacey KJ. Sester DP, et al. Among authors: masters sl. J Immunol. 2015 Aug 1;195(3):1233-41. doi: 10.4049/jimmunol.1402859. Epub 2015 Jun 26. J Immunol. 2015. PMID: 26116505
Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation.
Masters SL, Lagou V, Jéru I, Baker PJ, Van Eyck L, Parry DA, Lawless D, De Nardo D, Garcia-Perez JE, Dagley LF, Holley CL, Dooley J, Moghaddas F, Pasciuto E, Jeandel PY, Sciot R, Lyras D, Webb AI, Nicholson SE, De Somer L, van Nieuwenhove E, Ruuth-Praz J, Copin B, Cochet E, Medlej-Hashim M, Megarbane A, Schroder K, Savic S, Goris A, Amselem S, Wouters C, Liston A. Masters SL, et al. Sci Transl Med. 2016 Mar 30;8(332):332ra45. doi: 10.1126/scitranslmed.aaf1471. Sci Transl Med. 2016. PMID: 27030597 Free article.
Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner.
Conos SA, Chen KW, De Nardo D, Hara H, Whitehead L, Núñez G, Masters SL, Murphy JM, Schroder K, Vaux DL, Lawlor KE, Lindqvist LM, Vince JE. Conos SA, et al. Among authors: masters sl. Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):E961-E969. doi: 10.1073/pnas.1613305114. Epub 2017 Jan 17. Proc Natl Acad Sci U S A. 2017. PMID: 28096356 Free PMC article.
164 results