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Altered BCR and TLR signals promote enhanced positive selection of autoreactive transitional B cells in Wiskott-Aldrich syndrome.
Kolhatkar NS, Brahmandam A, Thouvenel CD, Becker-Herman S, Jacobs HM, Schwartz MA, Allenspach EJ, Khim S, Panigrahi AK, Luning Prak ET, Thrasher AJ, Notarangelo LD, Candotti F, Torgerson TR, Sanz I, Rawlings DJ. Kolhatkar NS, et al. Among authors: sanz i. J Exp Med. 2015 Sep 21;212(10):1663-77. doi: 10.1084/jem.20150585. Epub 2015 Sep 14. J Exp Med. 2015. PMID: 26371186 Free PMC article.
Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus.
Jenks SA, Cashman KS, Zumaquero E, Marigorta UM, Patel AV, Wang X, Tomar D, Woodruff MC, Simon Z, Bugrovsky R, Blalock EL, Scharer CD, Tipton CM, Wei C, Lim SS, Petri M, Niewold TB, Anolik JH, Gibson G, Lee FE, Boss JM, Lund FE, Sanz I. Jenks SA, et al. Among authors: sanz i. Immunity. 2018 Oct 16;49(4):725-739.e6. doi: 10.1016/j.immuni.2018.08.015. Epub 2018 Oct 9. Immunity. 2018. PMID: 30314758 Free PMC article.
Extrafollicular responses in humans and SLE.
Jenks SA, Cashman KS, Woodruff MC, Lee FE, Sanz I. Jenks SA, et al. Among authors: sanz i. Immunol Rev. 2019 Mar;288(1):136-148. doi: 10.1111/imr.12741. Immunol Rev. 2019. PMID: 30874345 Free PMC article. Review.
Autoantibody-mediated impairment of DNASE1L3 activity in sporadic systemic lupus erythematosus.
Hartl J, Serpas L, Wang Y, Rashidfarrokhi A, Perez OA, Sally B, Sisirak V, Soni C, Khodadadi-Jamayran A, Tsirigos A, Caiello I, Bracaglia C, Volpi S, Ghiggeri GM, Chida AS, Sanz I, Kim MY, Belmont HM, Silverman GJ, Clancy RM, Izmirly PM, Buyon JP, Reizis B. Hartl J, et al. Among authors: sanz i. J Exp Med. 2021 May 3;218(5):e20201138. doi: 10.1084/jem.20201138. J Exp Med. 2021. PMID: 33783474 Free PMC article.
Longitudinal studies of a B cell-derived signature of tolerance in renal transplant recipients.
Newell KA, Asare A, Sanz I, Wei C, Rosenberg A, Gao Z, Kanaparthi S, Asare S, Lim N, Stahly M, Howell M, Knechtle S, Kirk A, Marks WH, Kawai T, Spitzer T, Tolkoff-Rubin N, Sykes M, Sachs DH, Cosimi AB, Burlingham WJ, Phippard D, Turka LA. Newell KA, et al. Among authors: sanz i. Am J Transplant. 2015 Nov;15(11):2908-20. doi: 10.1111/ajt.13480. Epub 2015 Oct 13. Am J Transplant. 2015. PMID: 26461968 Free PMC article.
Failure of B Cell Tolerance in CVID.
Richardson CT, Slack MA, Dhillon G, Marcus CZ, Barnard J, Palanichamy A, Sanz I, Looney RJ, Anolik JH. Richardson CT, et al. Among authors: sanz i. Front Immunol. 2019 Dec 10;10:2881. doi: 10.3389/fimmu.2019.02881. eCollection 2019. Front Immunol. 2019. PMID: 31921145 Free PMC article. Clinical Trial.
310 results