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Targeting Th17 Effector Cytokines for the Treatment of Autoimmune Diseases.
Arch Immunol Ther Exp (Warsz). 2015 Dec;63(6):405-14. doi: 10.1007/s00005-015-0362-x. Epub 2015 Sep 10.
Arch Immunol Ther Exp (Warsz). 2015.
PMID: 26358867
Free article.
Review.
Targeting Th17 cells in autoimmune diseases.
Yang J, Sundrud MS, Skepner J, Yamagata T.
Yang J, et al. Among authors: skepner j.
Trends Pharmacol Sci. 2014 Oct;35(10):493-500. doi: 10.1016/j.tips.2014.07.006. Epub 2014 Aug 14.
Trends Pharmacol Sci. 2014.
PMID: 25131183
Review.
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Pharmacologic inhibition of RORγt regulates Th17 signature gene expression and suppresses cutaneous inflammation in vivo.
Skepner J, Ramesh R, Trocha M, Schmidt D, Baloglu E, Lobera M, Carlson T, Hill J, Orband-Miller LA, Barnes A, Boudjelal M, Sundrud M, Ghosh S, Yang J.
Skepner J, et al.
J Immunol. 2014 Mar 15;192(6):2564-75. doi: 10.4049/jimmunol.1302190. Epub 2014 Feb 10.
J Immunol. 2014.
PMID: 24516202
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In vivo regulation of gene expression and T helper type 17 differentiation by RORγt inverse agonists.
Skepner J, Trocha M, Ramesh R, Qu XA, Schmidt D, Baloglu E, Lobera M, Davis S, Nolan MA, Carlson TJ, Hill J, Ghosh S, Sundrud MS, Yang J.
Skepner J, et al.
Immunology. 2015 Jul;145(3):347-56. doi: 10.1111/imm.12444. Epub 2015 Apr 3.
Immunology. 2015.
PMID: 25604624
Free PMC article.
Item in Clipboard
Modulation of EZH2 expression in T cells improves efficacy of anti-CTLA-4 therapy.
Goswami S, Apostolou I, Zhang J, Skepner J, Anandhan S, Zhang X, Xiong L, Trojer P, Aparicio A, Subudhi SK, Allison JP, Zhao H, Sharma P.
Goswami S, et al. Among authors: skepner j.
J Clin Invest. 2018 Aug 31;128(9):3813-3818. doi: 10.1172/JCI99760. Epub 2018 Jul 30.
J Clin Invest. 2018.
PMID: 29905573
Free PMC article.
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Discovery of potent inhibitors of soluble epoxide hydrolase by combinatorial library design and structure-based virtual screening.
Xing L, McDonald JJ, Kolodziej SA, Kurumbail RG, Williams JM, Warren CJ, O'Neal JM, Skepner JE, Roberds SL.
Xing L, et al. Among authors: skepner je.
J Med Chem. 2011 Mar 10;54(5):1211-22. doi: 10.1021/jm101382t. Epub 2011 Feb 8.
J Med Chem. 2011.
PMID: 21302953
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Chronic treatment with epoxyeicosatrienoic acids modulates insulin signaling and prevents insulin resistance in hepatocytes.
Skepner JE, Shelly LD, Ji C, Reidich B, Luo Y.
Skepner JE, et al.
Prostaglandins Other Lipid Mediat. 2011 Feb;94(1-2):3-8. doi: 10.1016/j.prostaglandins.2010.10.002. Epub 2010 Oct 30.
Prostaglandins Other Lipid Mediat. 2011.
PMID: 21040800
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Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors.
Miller AA, Bundy GL, Mott JE, Skepner JE, Boyle TP, Harris DW, Hromockyj AE, Marotti KR, Zurenko GE, Munzner JB, Sweeney MT, Bammert GF, Hamel JC, Ford CW, Zhong WZ, Graber DR, Martin GE, Han F, Dolak LA, Seest EP, Ruble JC, Kamilar GM, Palmer JR, Banitt LS, Hurd AR, Barbachyn MR.
Miller AA, et al. Among authors: skepner je.
Antimicrob Agents Chemother. 2008 Aug;52(8):2806-12. doi: 10.1128/AAC.00247-08. Epub 2008 Jun 2.
Antimicrob Agents Chemother. 2008.
PMID: 18519725
Free PMC article.
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