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Ligand-Independent EGFR Signaling.
Guo G, Gong K, Wohlfeld B, Hatanpaa KJ, Zhao D, Habib AA. Guo G, et al. Among authors: hatanpaa kj. Cancer Res. 2015 Sep 1;75(17):3436-41. doi: 10.1158/0008-5472.CAN-15-0989. Epub 2015 Aug 17. Cancer Res. 2015. PMID: 26282175 Free PMC article. Review.
RIP1 activates PI3K-Akt via a dual mechanism involving NF-kappaB-mediated inhibition of the mTOR-S6K-IRS1 negative feedback loop and down-regulation of PTEN.
Park S, Zhao D, Hatanpaa KJ, Mickey BE, Saha D, Boothman DA, Story MD, Wong ET, Burma S, Georgescu MM, Rangnekar VM, Chauncey SS, Habib AA. Park S, et al. Among authors: hatanpaa kj. Cancer Res. 2009 May 15;69(10):4107-11. doi: 10.1158/0008-5472.CAN-09-0474. Epub 2009 May 12. Cancer Res. 2009. PMID: 19435890 Free PMC article.
EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma.
Mukherjee B, McEllin B, Camacho CV, Tomimatsu N, Sirasanagandala S, Nannepaga S, Hatanpaa KJ, Mickey B, Madden C, Maher E, Boothman DA, Furnari F, Cavenee WK, Bachoo RM, Burma S. Mukherjee B, et al. Among authors: hatanpaa kj. Cancer Res. 2009 May 15;69(10):4252-9. doi: 10.1158/0008-5472.CAN-08-4853. Epub 2009 May 12. Cancer Res. 2009. PMID: 19435898 Free PMC article.
An EGFR wild type-EGFRvIII-HB-EGF feed-forward loop regulates the activation of EGFRvIII.
Li L, Chakraborty S, Yang CR, Hatanpaa KJ, Cipher DJ, Puliyappadamba VT, Rehman A, Jiwani AJ, Mickey B, Madden C, Raisanen J, Burma S, Saha D, Wang Z, Pingle SC, Kesari S, Boothman DA, Habib AA. Li L, et al. Among authors: hatanpaa kj. Oncogene. 2014 Aug 14;33(33):4253-64. doi: 10.1038/onc.2013.400. Epub 2013 Sep 30. Oncogene. 2014. PMID: 24077285 Free PMC article.
EGFR wild type antagonizes EGFRvIII-mediated activation of Met in glioblastoma.
Li L, Puliyappadamba VT, Chakraborty S, Rehman A, Vemireddy V, Saha D, Souza RF, Hatanpaa KJ, Koduru P, Burma S, Boothman DA, Habib AA. Li L, et al. Among authors: hatanpaa kj. Oncogene. 2015 Jan 2;34(1):129-134. doi: 10.1038/onc.2013.534. Epub 2013 Dec 23. Oncogene. 2015. PMID: 24362532 Free PMC article.
144 results