Meinecke R - Search Results

1

One Question, Multiple Answers: Biochemical and Biophysical Screening Methods Retrieve Deviating Fragment Hit Lists.

Schiebel J, Radeva N, Köster H, Metz A, Krotzky T, Kuhnert M, Diederich WE, Heine A, Neumann L, Atmanene C, Roecklin D, Vivat-Hannah V, Renaud JP, Meinecke R, Schlinck N, Sitte A, Popp F, Zeeb M, Klebe G. Schiebel J, et al. Among authors: meinecke r. ChemMedChem. 2015 Sep;10(9):1511-21. doi: 10.1002/cmdc.201500267. Epub 2015 Aug 10. ChemMedChem. 2015. PMID: 26259992

2

A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I.

Ebenhoch R, Prinz S, Kaltwasser S, Mills DJ, Meinecke R, Rübbelke M, Reinert D, Bauer M, Weixler L, Zeeb M, Vonck J, Nar H. Ebenhoch R, et al. Among authors: meinecke r. Proc Natl Acad Sci U S A. 2020 Dec 15;117(50):31838-31849. doi: 10.1073/pnas.2013473117. Epub 2020 Nov 23. Proc Natl Acad Sci U S A. 2020. PMID: 33229582 Free PMC article.

3

Direct observation of ligand binding to membrane proteins in living cells by a saturation transfer double difference (STDD) NMR spectroscopy method shows a significantly higher affinity of integrin alpha(IIb)beta3 in native platelets than in liposomes.

Claasen B, Axmann M, Meinecke R, Meyer B. Claasen B, et al. Among authors: meinecke r. J Am Chem Soc. 2005 Jan 26;127(3):916-9. doi: 10.1021/ja044434w. J Am Chem Soc. 2005. PMID: 15656629

4

Saturation transfer difference NMR spectroscopy for identifying ligand epitopes and binding specificities.

Meyer B, Klein J, Mayer M, Meinecke R, Möller H, Neffe A, Schuster O, Wülfken J, Ding Y, Knaie O, Labbe J, Palcic MM, Hindsgaul O, Wagner B, Ernst B. Meyer B, et al. Among authors: meinecke r. Ernst Schering Res Found Workshop. 2004;(44):149-67. doi: 10.1007/978-3-662-05397-3_9. Ernst Schering Res Found Workshop. 2004. PMID: 14579779 Review. No abstract available.

5

Determination of the binding specificity of an integral membrane protein by saturation transfer difference NMR: RGD peptide ligands binding to integrin alphaIIbbeta3.

Meinecke R, Meyer B. Meinecke R, et al. J Med Chem. 2001 Sep 13;44(19):3059-65. doi: 10.1021/jm0109154. J Med Chem. 2001. PMID: 11543674

6

Fraser (Cryptophthalmos-syndactyly) syndrome: a case with bilateral anophthalmia but presence of normal eyelids.

Pankau R, Partsch CJ, Jänig U, Meinecke R. Pankau R, et al. Among authors: meinecke r. Genet Couns. 1994;5(2):191-4. Genet Couns. 1994. PMID: 7917132

7

Multiple malformation syndrome including cleft lip and palate and cardiac abnormalities due to an interstitial deletion of chromosome 12q.

Meinecke P, Meinecke R. Meinecke P, et al. Among authors: meinecke r. J Med Genet. 1987 Mar;24(3):187. doi: 10.1136/jmg.24.3.187. J Med Genet. 1987. PMID: 3573007 Free PMC article. No abstract available.

8

[Specialty documentation in orthopedic outpatient clinics].

Schulze KJ, Winde I, Schneider HJ, Stelzner A, Runge H, Meinecke R, Kratzsch J, Dethoff E, Buchmann J. Schulze KJ, et al. Among authors: meinecke r. Z Arztl Fortbild (Jena). 1978 Aug 15;72(16):777-83. Z Arztl Fortbild (Jena). 1978. PMID: 716485 German. No abstract available.

9

[Therapy of osteogenesis imperfecta].

Meinecke R. Meinecke R. Beitr Orthop Traumatol. 1978 May;25(5):276-81. Beitr Orthop Traumatol. 1978. PMID: 678282 German. No abstract available.

10

[Hyperostosis of the iliac crest. Anatomo-radiologic features].

Lagier R, Meinecke R. Lagier R, et al. Among authors: meinecke r. Rev Rhum Mal Osteoartic. 1977 Feb;44(2):131-4. Rev Rhum Mal Osteoartic. 1977. PMID: 847362 French.

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