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Design, synthesis, and crystal structures of 6-alkylidene-2'-substituted penicillanic acid sulfones as potent inhibitors of Acinetobacter baumannii OXA-24 carbapenemase.
Bou G, Santillana E, Sheri A, Beceiro A, Sampson JM, Kalp M, Bethel CR, Distler AM, Drawz SM, Pagadala SR, van den Akker F, Bonomo RA, Romero A, Buynak JD. Bou G, et al. Among authors: beceiro a. J Am Chem Soc. 2010 Sep 29;132(38):13320-31. doi: 10.1021/ja104092z. J Am Chem Soc. 2010. PMID: 20822105 Free PMC article.
LN-1-255, a penicillanic acid sulfone able to inhibit the class D carbapenemase OXA-48.
Vallejo JA, Martínez-Guitián M, Vázquez-Ucha JC, González-Bello C, Poza M, Buynak JD, Bethel CR, Bonomo RA, Bou G, Beceiro A. Vallejo JA, et al. Among authors: beceiro a. J Antimicrob Chemother. 2016 Aug;71(8):2171-80. doi: 10.1093/jac/dkw105. Epub 2016 Apr 28. J Antimicrob Chemother. 2016. PMID: 27125555 Free PMC article.
Synergy between Colistin and the Signal Peptidase Inhibitor MD3 Is Dependent on the Mechanism of Colistin Resistance in Acinetobacter baumannii.
Martínez-Guitián M, Vázquez-Ucha JC, Odingo J, Parish T, Poza M, Waite RD, Bou G, Wareham DW, Beceiro A. Martínez-Guitián M, et al. Among authors: beceiro a. Antimicrob Agents Chemother. 2016 Jun 20;60(7):4375-9. doi: 10.1128/AAC.00510-16. Print 2016 Jul. Antimicrob Agents Chemother. 2016. PMID: 27139471 Free PMC article.
Activity of the β-Lactamase Inhibitor LN-1-255 against Carbapenem-Hydrolyzing Class D β-Lactamases from Acinetobacter baumannii.
Vázquez-Ucha JC, Maneiro M, Martínez-Guitián M, Buynak J, Bethel CR, Bonomo RA, Bou G, Poza M, González-Bello C, Beceiro A. Vázquez-Ucha JC, et al. Among authors: beceiro a. Antimicrob Agents Chemother. 2017 Oct 24;61(11):e01172-17. doi: 10.1128/AAC.01172-17. Print 2017 Nov. Antimicrob Agents Chemother. 2017. PMID: 28807908 Free PMC article.
83 results