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Lead Exposure during Early Human Development and DNA Methylation of Imprinted Gene Regulatory Elements in Adulthood.
Li Y, Xie C, Murphy SK, Skaar D, Nye M, Vidal AC, Cecil KM, Dietrich KN, Puga A, Jirtle RL, Hoyo C. Li Y, et al. Among authors: puga a. Environ Health Perspect. 2016 May;124(5):666-73. doi: 10.1289/ehp.1408577. Epub 2015 Jun 26. Environ Health Perspect. 2016. PMID: 26115033 Free PMC article.
RESULTS: Mean blood lead concentration from birth to 78 months was associated with a significant decrease in PEG3 DMR methylation (beta = -0.0014; 95% CI: -0.0023, -0.0005, p = 0.002), stronger in males (beta = -0.0024; 95% CI: -0.0038, -0.0009, p = 0.003) than in females …
RESULTS: Mean blood lead concentration from birth to 78 months was associated with a significant decrease in PEG3 DMR methylation (be …
Prenatal and early postnatal lead exposure in mice: neuroimaging findings.
Lindquist DM, Beckwith T, Cecil KM, Sánchez-Martín FJ, Landero-Figueroa J, Puga A. Lindquist DM, et al. Among authors: puga a. Quant Imaging Med Surg. 2015 Aug;5(4):511-8. doi: 10.3978/j.issn.2223-4292.2015.07.01. Quant Imaging Med Surg. 2015. PMID: 26435914 Free PMC article.
Disruption of aryl hydrocarbon receptor homeostatic levels during embryonic stem cell differentiation alters expression of homeobox transcription factors that control cardiomyogenesis.
Wang Q, Chen J, Ko CI, Fan Y, Carreira V, Chen Y, Xia Y, Medvedovic M, Puga A. Wang Q, et al. Among authors: puga a. Environ Health Perspect. 2013 Nov-Dec;121(11-12):1334-43. doi: 10.1289/ehp.1307297. Epub 2013 Sep 20. Environ Health Perspect. 2013. PMID: 24058054 Free PMC article.
Genomewide analysis of aryl hydrocarbon receptor binding targets reveals an extensive array of gene clusters that control morphogenetic and developmental programs.
Sartor MA, Schnekenburger M, Marlowe JL, Reichard JF, Wang Y, Fan Y, Ma C, Karyala S, Halbleib D, Liu X, Medvedovic M, Puga A. Sartor MA, et al. Among authors: puga a. Environ Health Perspect. 2009 Jul;117(7):1139-46. doi: 10.1289/ehp.0800485. Epub 2009 Mar 24. Environ Health Perspect. 2009. PMID: 19654925 Free PMC article.
391 results