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A finely tuned interplay between calcium binding, ionic strength and pH modulates conformational and oligomerization equilibria in the Respiratory Syncytial Virus Matrix (M) protein.
Esperante SA, Alvarez-Paggi D, Salgueiro M, Desimone MF, de Oliveira GAP, Arán M, García-Pardo J, Aptekmann AA, Ventura S, Alonso LG, de Prat-Gay G. Esperante SA, et al. Among authors: de prat gay g. Arch Biochem Biophys. 2022 Nov 30;731:109424. doi: 10.1016/j.abb.2022.109424. Epub 2022 Oct 8. Arch Biochem Biophys. 2022. PMID: 36220378
Conformational buffering underlies functional selection in intrinsically disordered protein regions.
González-Foutel NS, Glavina J, Borcherds WM, Safranchik M, Barrera-Vilarmau S, Sagar A, Estaña A, Barozet A, Garrone NA, Fernandez-Ballester G, Blanes-Mira C, Sánchez IE, de Prat-Gay G, Cortés J, Bernadó P, Pappu RV, Holehouse AS, Daughdrill GW, Chemes LB. González-Foutel NS, et al. Among authors: de prat gay g. Nat Struct Mol Biol. 2022 Aug;29(8):781-790. doi: 10.1038/s41594-022-00811-w. Epub 2022 Aug 10. Nat Struct Mol Biol. 2022. PMID: 35948766 Free PMC article.
Deconstructing virus condensation.
Lopez N, Camporeale G, Salgueiro M, Borkosky SS, Visentín A, Peralta-Martinez R, Loureiro ME, de Prat-Gay G. Lopez N, et al. Among authors: de prat gay g. PLoS Pathog. 2021 Oct 14;17(10):e1009926. doi: 10.1371/journal.ppat.1009926. eCollection 2021 Oct. PLoS Pathog. 2021. PMID: 34648608 Free PMC article. Review.
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