Bennett CF - Search Results

1

DICER/AGO-dependent epigenetic silencing of D4Z4 repeats enhanced by exogenous siRNA suggests mechanisms and therapies for FSHD.

Lim JW, Snider L, Yao Z, Tawil R, Van Der Maarel SM, Rigo F, Bennett CF, Filippova GN, Tapscott SJ. Lim JW, et al. Among authors: bennett cf. Hum Mol Genet. 2015 Sep 1;24(17):4817-28. doi: 10.1093/hmg/ddv206. Epub 2015 Jun 3. Hum Mol Genet. 2015. PMID: 26041815 Free PMC article.

2

Synthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicing.

Rigo F, Hua Y, Chun SJ, Prakash TP, Krainer AR, Bennett CF. Rigo F, et al. Among authors: bennett cf. Nat Chem Biol. 2012 Apr 15;8(6):555-61. doi: 10.1038/nchembio.939. Nat Chem Biol. 2012. PMID: 22504300 Free PMC article.

3

Antisense-based therapy for the treatment of spinal muscular atrophy.

Rigo F, Hua Y, Krainer AR, Bennett CF. Rigo F, et al. Among authors: bennett cf. J Cell Biol. 2012 Oct 1;199(1):21-5. doi: 10.1083/jcb.201207087. J Cell Biol. 2012. PMID: 23027901 Free PMC article.

4

Manipulation of PK-M mutually exclusive alternative splicing by antisense oligonucleotides.

Wang Z, Jeon HY, Rigo F, Bennett CF, Krainer AR. Wang Z, et al. Among authors: bennett cf. Open Biol. 2012 Oct;2(10):120133. doi: 10.1098/rsob.120133. Open Biol. 2012. PMID: 23155487 Free PMC article.

5

Pathological impact of SMN2 mis-splicing in adult SMA mice.

Sahashi K, Ling KK, Hua Y, Wilkinson JE, Nomakuchi T, Rigo F, Hung G, Xu D, Jiang YP, Lin RZ, Ko CP, Bennett CF, Krainer AR. Sahashi K, et al. Among authors: bennett cf. EMBO Mol Med. 2013 Oct;5(10):1586-601. doi: 10.1002/emmm.201302567. Epub 2013 Sep 9. EMBO Mol Med. 2013. PMID: 24014320 Free PMC article.

6

Nonsense-mediated decay as a terminating mechanism for antisense oligonucleotides.

Ward AJ, Norrbom M, Chun S, Bennett CF, Rigo F. Ward AJ, et al. Among authors: bennett cf. Nucleic Acids Res. 2014 May;42(9):5871-9. doi: 10.1093/nar/gku184. Epub 2014 Mar 3. Nucleic Acids Res. 2014. PMID: 24589581 Free PMC article.

7

Pharmacology of a central nervous system delivered 2'-O-methoxyethyl-modified survival of motor neuron splicing oligonucleotide in mice and nonhuman primates.

Rigo F, Chun SJ, Norris DA, Hung G, Lee S, Matson J, Fey RA, Gaus H, Hua Y, Grundy JS, Krainer AR, Henry SP, Bennett CF. Rigo F, et al. Among authors: bennett cf. J Pharmacol Exp Ther. 2014 Jul;350(1):46-55. doi: 10.1124/jpet.113.212407. Epub 2014 Apr 30. J Pharmacol Exp Ther. 2014. PMID: 24784568 Free PMC article.

8

Antisense oligonucleotide-based therapies for diseases caused by pre-mRNA processing defects.

Rigo F, Seth PP, Bennett CF. Rigo F, et al. Among authors: bennett cf. Adv Exp Med Biol. 2014;825:303-52. doi: 10.1007/978-1-4939-1221-6_9. Adv Exp Med Biol. 2014. PMID: 25201110 Review.

9

Towards a therapy for Angelman syndrome by targeting a long non-coding RNA.

Meng L, Ward AJ, Chun S, Bennett CF, Beaudet AL, Rigo F. Meng L, et al. Among authors: bennett cf. Nature. 2015 Feb 19;518(7539):409-12. doi: 10.1038/nature13975. Epub 2014 Dec 1. Nature. 2015. PMID: 25470045 Free PMC article.

10

Motor neuron cell-nonautonomous rescue of spinal muscular atrophy phenotypes in mild and severe transgenic mouse models.

Hua Y, Liu YH, Sahashi K, Rigo F, Bennett CF, Krainer AR. Hua Y, et al. Among authors: bennett cf. Genes Dev. 2015 Feb 1;29(3):288-97. doi: 10.1101/gad.256644.114. Epub 2015 Jan 12. Genes Dev. 2015. PMID: 25583329 Free PMC article.

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