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Design and Synthesis of Tubulin and Histone Deacetylase Inhibitor Based on iso-Combretastatin A-4.
Lamaa D, Lin HP, Zig L, Bauvais C, Bollot G, Bignon J, Levaique H, Pamlard O, Dubois J, Ouaissi M, Souce M, Kasselouri A, Saller F, Borgel D, Jayat-Vignoles C, Al-Mouhammad H, Feuillard J, Benihoud K, Alami M, Hamze A. Lamaa D, et al. Among authors: levaique h. J Med Chem. 2018 Aug 9;61(15):6574-6591. doi: 10.1021/acs.jmedchem.8b00050. Epub 2018 Jul 26. J Med Chem. 2018. PMID: 30004697
1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin-Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation.
Naret T, Khelifi I, Provot O, Bignon J, Levaique H, Dubois J, Souce M, Kasselouri A, Deroussent A, Paci A, Varela PF, Gigant B, Alami M, Hamze A. Naret T, et al. Among authors: levaique h. J Med Chem. 2019 Feb 28;62(4):1902-1916. doi: 10.1021/acs.jmedchem.8b01386. Epub 2018 Dec 21. J Med Chem. 2019. PMID: 30525602
Cyclic bridged analogs of isoCA-4: Design, synthesis and biological evaluation.
Pecnard S, Provot O, Levaique H, Bignon J, Askenatzis L, Saller F, Borgel D, Michallet S, Laisne MC, Lafanechère L, Alami M, Hamze A. Pecnard S, et al. Among authors: levaique h. Eur J Med Chem. 2021 Jan 1;209:112873. doi: 10.1016/j.ejmech.2020.112873. Epub 2020 Oct 4. Eur J Med Chem. 2021. PMID: 33038796
18 results