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NEU1 sialidase expressed in human airway epithelia regulates epidermal growth factor receptor (EGFR) and MUC1 protein signaling.
Lillehoj EP, Hyun SW, Feng C, Zhang L, Liu A, Guang W, Nguyen C, Luzina IG, Atamas SP, Passaniti A, Twaddell WS, Puché AC, Wang LX, Cross AS, Goldblum SE. Lillehoj EP, et al. Among authors: goldblum se. J Biol Chem. 2012 Mar 9;287(11):8214-31. doi: 10.1074/jbc.M111.292888. Epub 2012 Jan 13. J Biol Chem. 2012. PMID: 22247545 Free PMC article.
NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does not.
Cross AS, Hyun SW, Miranda-Ribera A, Feng C, Liu A, Nguyen C, Zhang L, Luzina IG, Atamas SP, Twaddell WS, Guang W, Lillehoj EP, Puché AC, Huang W, Wang LX, Passaniti A, Goldblum SE. Cross AS, et al. Among authors: goldblum se. J Biol Chem. 2012 May 4;287(19):15966-80. doi: 10.1074/jbc.M112.346817. Epub 2012 Mar 8. J Biol Chem. 2012. PMID: 22403397 Free PMC article.
NEU1 sialidase regulates the sialylation state of CD31 and disrupts CD31-driven capillary-like tube formation in human lung microvascular endothelia.
Lee C, Liu A, Miranda-Ribera A, Hyun SW, Lillehoj EP, Cross AS, Passaniti A, Grimm PR, Kim BY, Welling PA, Madri JA, DeLisser HM, Goldblum SE. Lee C, et al. Among authors: goldblum se. J Biol Chem. 2014 Mar 28;289(13):9121-35. doi: 10.1074/jbc.M114.555888. Epub 2014 Feb 18. J Biol Chem. 2014. PMID: 24550400 Free PMC article.
The NEU1-selective sialidase inhibitor, C9-butyl-amide-DANA, blocks sialidase activity and NEU1-mediated bioactivities in human lung in vitro and murine lung in vivo.
Hyun SW, Liu A, Liu Z, Cross AS, Verceles AC, Magesh S, Kommagalla Y, Kona C, Ando H, Luzina IG, Atamas SP, Piepenbrink KH, Sundberg EJ, Guang W, Ishida H, Lillehoj EP, Goldblum SE. Hyun SW, et al. Among authors: goldblum se. Glycobiology. 2016 Aug;26(8):834-49. doi: 10.1093/glycob/cww060. Epub 2016 May 25. Glycobiology. 2016. PMID: 27226251 Free PMC article.
94 results