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A multi-targeted approach to suppress tumor-promoting inflammation.
Samadi AK, Bilsland A, Georgakilas AG, Amedei A, Amin A, Bishayee A, Azmi AS, Lokeshwar BL, Grue B, Panis C, Boosani CS, Poudyal D, Stafforini DM, Bhakta D, Niccolai E, Guha G, Vasantha Rupasinghe HP, Fujii H, Honoki K, Mehta K, Aquilano K, Lowe L, Hofseth LJ, Ricciardiello L, Ciriolo MR, Singh N, Whelan RL, Chaturvedi R, Ashraf SS, Shantha Kumara HMC, Nowsheen S, Mohammed SI, Keith WN, Helferich WG, Yang X. Samadi AK, et al. Among authors: whelan rl. Semin Cancer Biol. 2015 Dec;35 Suppl:S151-S184. doi: 10.1016/j.semcancer.2015.03.006. Epub 2015 May 5. Semin Cancer Biol. 2015. PMID: 25951989 Free PMC article. Review.
Colorectal resection, both open and laparoscopic-assisted, in patients with benign indications is associated with proangiogenic changes in plasma angiopoietin 1 and 2 levels.
Shantha Kumara HM, Hoffman A, Kim IY, Feingold D, Dujovny N, Kalady M, Luchtefeld M, Whelan RL. Shantha Kumara HM, et al. Among authors: whelan rl. Surg Endosc. 2009 Feb;23(2):409-15. doi: 10.1007/s00464-008-0132-5. Epub 2008 Sep 24. Surg Endosc. 2009. PMID: 18813991 Clinical Trial.
Minimally invasive colon resection for malignant colonic conditions is associated with a transient early increase in plasma sVEGFR1 and a decrease in sVEGFR2 levels after surgery.
Shantha Kumara HM, Cabot JC, Hoffman A, Luchtefeld M, Kalady MF, Hyman N, Feingold D, Baxter R, Whelan RL. Shantha Kumara HM, et al. Among authors: whelan rl. Surg Endosc. 2010 Feb;24(2):283-9. doi: 10.1007/s00464-009-0575-3. Epub 2009 Jun 24. Surg Endosc. 2010. PMID: 19551437
Minimally invasive colorectal resection for cancer is associated with a short-lived decrease in soluble Tie-2 receptor levels, which may transiently inhibit VEGF-mediated angiogenesis (via altered blood levels of free Ang-1 and Ang-2).
Shantha Kumara HM, Grieco MJ, Yan X, Kalady MF, DiMaggio V, Kim DG, Hyman N, Feingold DL, Whelan RL. Shantha Kumara HM, et al. Among authors: whelan rl. Surg Endosc. 2010 Oct;24(10):2581-7. doi: 10.1007/s00464-010-1008-z. Epub 2010 Mar 31. Surg Endosc. 2010. PMID: 20354881
167 results