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The neuron-derived orphan receptor 1 (NOR1) is induced upon human alternative macrophage polarization and stimulates the expression of markers of the M2 phenotype.
De Paoli F, Eeckhoute J, Copin C, Vanhoutte J, Duhem C, Derudas B, Dubois-Chevalier J, Colin S, Zawadzki C, Jude B, Haulon S, Lefebvre P, Staels B, Chinetti-Gbaguidi G. De Paoli F, et al. Among authors: vanhoutte j. Atherosclerosis. 2015 Jul;241(1):18-26. doi: 10.1016/j.atherosclerosis.2015.04.798. Epub 2015 Apr 26. Atherosclerosis. 2015. PMID: 25941992
Liver X receptor activation stimulates iron export in human alternative macrophages.
Bories G, Colin S, Vanhoutte J, Derudas B, Copin C, Fanchon M, Daoudi M, Belloy L, Haulon S, Zawadzki C, Jude B, Staels B, Chinetti-Gbaguidi G. Bories G, et al. Among authors: vanhoutte j. Circ Res. 2013 Nov 8;113(11):1196-205. doi: 10.1161/CIRCRESAHA.113.301656. Epub 2013 Sep 13. Circ Res. 2013. PMID: 24036496 Free PMC article.
Transducin-like enhancer of split-1 is expressed and functional in human macrophages.
De Paoli F, Copin C, Vanhoutte J, Derudas B, Vinod M, Zawadzki C, Susen S, Pattou F, Haulon S, Staels B, Eeckhoute J, Chinetti-Gbaguidi G. De Paoli F, et al. Among authors: vanhoutte j. FEBS Lett. 2016 Jan;590(1):43-52. doi: 10.1002/1873-3468.12029. Epub 2015 Dec 30. FEBS Lett. 2016. PMID: 26763127 Free article.
The novel selective PPARα modulator (SPPARMα) pemafibrate improves dyslipidemia, enhances reverse cholesterol transport and decreases inflammation and atherosclerosis.
Hennuyer N, Duplan I, Paquet C, Vanhoutte J, Woitrain E, Touche V, Colin S, Vallez E, Lestavel S, Lefebvre P, Staels B. Hennuyer N, et al. Among authors: vanhoutte j. Atherosclerosis. 2016 Jun;249:200-8. doi: 10.1016/j.atherosclerosis.2016.03.003. Epub 2016 Mar 4. Atherosclerosis. 2016. PMID: 27108950
Human atherosclerotic plaque alternative macrophages display low cholesterol handling but high phagocytosis because of distinct activities of the PPARγ and LXRα pathways.
Chinetti-Gbaguidi G, Baron M, Bouhlel MA, Vanhoutte J, Copin C, Sebti Y, Derudas B, Mayi T, Bories G, Tailleux A, Haulon S, Zawadzki C, Jude B, Staels B. Chinetti-Gbaguidi G, et al. Among authors: vanhoutte j. Circ Res. 2011 Apr 15;108(8):985-95. doi: 10.1161/CIRCRESAHA.110.233775. Epub 2011 Feb 24. Circ Res. 2011. PMID: 21350215 Free PMC article.
p16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages.
Cudejko C, Wouters K, Fuentes L, Hannou SA, Paquet C, Bantubungi K, Bouchaert E, Vanhoutte J, Fleury S, Remy P, Tailleux A, Chinetti-Gbaguidi G, Dombrowicz D, Staels B, Paumelle R. Cudejko C, et al. Among authors: vanhoutte j. Blood. 2011 Sep 1;118(9):2556-66. doi: 10.1182/blood-2010-10-313106. Epub 2011 Jun 2. Blood. 2011. PMID: 21636855 Free PMC article.
Human Alternative Macrophages Populate Calcified Areas of Atherosclerotic Lesions and Display Impaired RANKL-Induced Osteoclastic Bone Resorption Activity.
Chinetti-Gbaguidi G, Daoudi M, Rosa M, Vinod M, Louvet L, Copin C, Fanchon M, Vanhoutte J, Derudas B, Belloy L, Haulon S, Zawadzki C, Susen S, Massy ZA, Eeckhoute J, Staels B. Chinetti-Gbaguidi G, et al. Among authors: vanhoutte j. Circ Res. 2017 Jun 23;121(1):19-30. doi: 10.1161/CIRCRESAHA.116.310262. Epub 2017 Apr 24. Circ Res. 2017. PMID: 28438779
The tumour suppressor CDKN2A/p16INK4a regulates adipogenesis and bone marrow-dependent development of perivascular adipose tissue.
Wouters K, Deleye Y, Hannou SA, Vanhoutte J, Maréchal X, Coisne A, Tagzirt M, Derudas B, Bouchaert E, Duhem C, Vallez E, Schalkwijk CG, Pattou F, Montaigne D, Staels B, Paumelle R. Wouters K, et al. Among authors: vanhoutte j. Diab Vasc Dis Res. 2017 Nov;14(6):516-524. doi: 10.1177/1479164117728012. Epub 2017 Sep 2. Diab Vasc Dis Res. 2017. PMID: 28868898 Free PMC article.
Nuclear Receptor Subfamily 1 Group D Member 1 Regulates Circadian Activity of NLRP3 Inflammasome to Reduce the Severity of Fulminant Hepatitis in Mice.
Pourcet B, Zecchin M, Ferri L, Beauchamp J, Sitaula S, Billon C, Delhaye S, Vanhoutte J, Mayeuf-Louchart A, Thorel Q, Haas JT, Eeckhoute J, Dombrowicz D, Duhem C, Boulinguiez A, Lancel S, Sebti Y, Burris TP, Staels B, Duez HM. Pourcet B, et al. Among authors: vanhoutte j. Gastroenterology. 2018 Apr;154(5):1449-1464.e20. doi: 10.1053/j.gastro.2017.12.019. Epub 2017 Dec 24. Gastroenterology. 2018. PMID: 29277561 Free PMC article.
57 results