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Animal models of Parkinson׳s disease: Effects of two adenosine A2A receptor antagonists ST4206 and ST3932, metabolites of 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535).
Stasi MA, Minetti P, Lombardo K, Riccioni T, Caprioli A, Vertechy M, Di Serio S, Pace S, Borsini F. Stasi MA, et al. Among authors: minetti p. Eur J Pharmacol. 2015 Aug 15;761:353-61. doi: 10.1016/j.ejphar.2015.03.070. Epub 2015 Apr 30. Eur J Pharmacol. 2015. PMID: 25936513
ST 1535: a preferential A2A adenosine receptor antagonist.
Stasi MA, Borsini F, Varani K, Vincenzi F, Di Cesare MA, Minetti P, Ghirardi O, Carminati P. Stasi MA, et al. Among authors: minetti p. Int J Neuropsychopharmacol. 2006 Oct;9(5):575-84. doi: 10.1017/S1461145705006188. Epub 2005 Nov 23. Int J Neuropsychopharmacol. 2006. PMID: 16867213 Free article.
Synthesis and biological evaluation of metabolites of 2-n-butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535), a potent antagonist of the A2A adenosine receptor for the treatment of Parkinson's disease.
Piersanti G, Bartoccini F, Lucarini S, Cabri W, Stasi MA, Riccioni T, Borsini F, Tarzia G, Minetti P. Piersanti G, et al. Among authors: minetti p. J Med Chem. 2013 Jul 11;56(13):5456-63. doi: 10.1021/jm400491x. Epub 2013 Jun 24. J Med Chem. 2013. PMID: 23789814
ST2472: a new potential antipsychotic with very low liability to induce side-effects.
Stasi MA, Di Serio S, Vertechy M, Schiavone A, Ghirardi O, Minetti P, Campiani G, Borsini F, Carminati P. Stasi MA, et al. Among authors: minetti p. Int J Neuropsychopharmacol. 2008 May;11(3):309-19. doi: 10.1017/S146114570700805X. Epub 2007 Oct 10. Int J Neuropsychopharmacol. 2008. PMID: 17925059 Free article.
Pyrrolo[1,3]benzothiazepine-based serotonin and dopamine receptor antagonists. Molecular modeling, further structure-activity relationship studies, and identification of novel atypical antipsychotic agents.
Campiani G, Butini S, Fattorusso C, Catalanotti B, Gemma S, Nacci V, Morelli E, Cagnotto A, Mereghetti I, Mennini T, Carli M, Minetti P, Di Cesare MA, Mastroianni D, Scafetta N, Galletti B, Stasi MA, Castorina M, Pacifici L, Vertechy M, Di Serio S, Ghirardi O, Tinti O, Carminati P. Campiani G, et al. Among authors: minetti p. J Med Chem. 2004 Jan 1;47(1):143-57. doi: 10.1021/jm0309811. J Med Chem. 2004. PMID: 14695828
24 results