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Animal models of Parkinson׳s disease: Effects of two adenosine A2A receptor antagonists ST4206 and ST3932, metabolites of 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535).
Stasi MA, Minetti P, Lombardo K, Riccioni T, Caprioli A, Vertechy M, Di Serio S, Pace S, Borsini F. Stasi MA, et al. Among authors: caprioli a. Eur J Pharmacol. 2015 Aug 15;761:353-61. doi: 10.1016/j.ejphar.2015.03.070. Epub 2015 Apr 30. Eur J Pharmacol. 2015. PMID: 25936513
Discovery of potent inhibitors of human and mouse fatty acid amide hydrolases.
Butini S, Brindisi M, Gemma S, Minetti P, Cabri W, Gallo G, Vincenti S, Talamonti E, Borsini F, Caprioli A, Stasi MA, Di Serio S, Ros S, Borrelli G, Maramai S, Fezza F, Campiani G, Maccarrone M. Butini S, et al. Among authors: caprioli a. J Med Chem. 2012 Aug 9;55(15):6898-915. doi: 10.1021/jm300689c. Epub 2012 Jul 26. J Med Chem. 2012. PMID: 22779702
An inhibitor of neuronal exocytosis (DD04107) displays long-lasting in vivo activity against chronic inflammatory and neuropathic pain.
Ponsati B, Carreño C, Curto-Reyes V, Valenzuela B, Duart MJ, Van den Nest W, Cauli O, Beltran B, Fernandez J, Borsini F, Caprioli A, Di Serio S, Veretchy M, Baamonde A, Menendez L, Barros F, de la Pena P, Borges R, Felipo V, Planells-Cases R, Ferrer-Montiel A. Ponsati B, et al. Among authors: caprioli a. J Pharmacol Exp Ther. 2012 Jun;341(3):634-45. doi: 10.1124/jpet.111.190678. Epub 2012 Mar 5. J Pharmacol Exp Ther. 2012. PMID: 22393248 Free article.
Enol carbamates as inhibitors of fatty acid amide hydrolase (FAAH) endowed with high selectivity for FAAH over the other targets of the endocannabinoid system.
Gattinoni S, De Simone C, Dallavalle S, Fezza F, Nannei R, Amadio D, Minetti P, Quattrociocchi G, Caprioli A, Borsini F, Cabri W, Penco S, Merlini L, Maccarrone M. Gattinoni S, et al. Among authors: caprioli a. ChemMedChem. 2010 Mar 1;5(3):357-60. doi: 10.1002/cmdc.200900472. ChemMedChem. 2010. PMID: 20112328 No abstract available.
Olanzapine (LY170053, 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine), but not the novel atypical antipsychotic ST2472 (9-piperazin-1-ylpyrrolo[2,1-b][1,3]benzothiazepine), chronic administration induces weight gain, hyperphagia, and metabolic dysregulation in mice.
Coccurello R, Caprioli A, Conti R, Ghirardi O, Borsini F, Carminati P, Moles A. Coccurello R, et al. Among authors: caprioli a. J Pharmacol Exp Ther. 2008 Sep;326(3):905-11. doi: 10.1124/jpet.108.137240. Epub 2008 Jun 20. J Pharmacol Exp Ther. 2008. PMID: 18567835
A new group of oxime carbamates as reversible inhibitors of fatty acid amide hydrolase.
Gattinoni S, Simone CD, Dallavalle S, Fezza F, Nannei R, Battista N, Minetti P, Quattrociocchi G, Caprioli A, Borsini F, Cabri W, Penco S, Merlini L, Maccarrone M. Gattinoni S, et al. Among authors: caprioli a. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4406-11. doi: 10.1016/j.bmcl.2010.06.050. Epub 2010 Jun 15. Bioorg Med Chem Lett. 2010. PMID: 20591666
243 results