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In Vitro and In Vivo Evaluation of Cysteine Rebridged Trastuzumab-MMAE Antibody Drug Conjugates with Defined Drug-to-Antibody Ratios.
Bryant P, Pabst M, Badescu G, Bird M, McDowell W, Jamieson E, Swierkosz J, Jurlewicz K, Tommasi R, Henseleit K, Sheng X, Camper N, Manin A, Kozakowska K, Peciak K, Laurine E, Grygorash R, Kyle A, Morris D, Parekh V, Abhilash A, Choi JW, Edwards J, Frigerio M, Baker MP, Godwin A. Bryant P, et al. Among authors: pabst m. Mol Pharm. 2015 Jun 1;12(6):1872-9. doi: 10.1021/acs.molpharmaceut.5b00116. Epub 2015 May 5. Mol Pharm. 2015. PMID: 25894424
Modulation of drug-linker design to enhance in vivo potency of homogeneous antibody-drug conjugates.
Pabst M, McDowell W, Manin A, Kyle A, Camper N, De Juan E, Parekh V, Rudge F, Makwana H, Kantner T, Parekh H, Michelet A, Sheng X, Popa G, Tucker C, Khayrzad F, Pollard D, Kozakowska K, Resende R, Jenkins A, Simoes F, Morris D, Williams P, Badescu G, Baker MP, Bird M, Frigerio M, Godwin A. Pabst M, et al. J Control Release. 2017 May 10;253:160-164. doi: 10.1016/j.jconrel.2017.02.027. Epub 2017 Mar 1. J Control Release. 2017. PMID: 28257988
Incorporation of Hydrophilic Macrocycles Into Drug-Linker Reagents Produces Antibody-Drug Conjugates With Enhanced in vivo Performance.
Evans N, Grygorash R, Williams P, Kyle A, Kantner T, Pathak R, Sheng X, Simoes F, Makwana H, Resende R, de Juan E, Jenkins A, Morris D, Michelet A, Jewitt F, Rudge F, Camper N, Manin A, McDowell W, Pabst M, Godwin A, Frigerio M, Bird M. Evans N, et al. Among authors: pabst m. Front Pharmacol. 2022 Jun 17;13:764540. doi: 10.3389/fphar.2022.764540. eCollection 2022. Front Pharmacol. 2022. PMID: 35784686 Free PMC article.
Craspase Orthologs Cleave a Nonconserved Site in Target Protein Csx30.
van Beljouw SPB, Haagsma AC, Kalogeropoulos K, Pabst M, Brouns SJJ. van Beljouw SPB, et al. Among authors: pabst m. ACS Chem Biol. 2024 May 17;19(5):1051-1055. doi: 10.1021/acschembio.3c00788. Epub 2024 Apr 11. ACS Chem Biol. 2024. PMID: 38602884 Free PMC article.
Correction: Trichlorobacter ammonificans, a dedicated acetate-dependent ammonifier with a novel module for dissimilatory nitrate reduction to ammonia.
Sorokin DY, Tikhonova TV, Koch H, van den Berg EM, Hinderks RS, Pabst M, Dergousova NI, Solovevac AY, Kuenen GJ, Popov VO, van Loosdrecht MCM, Lücker S. Sorokin DY, et al. Among authors: pabst m. ISME J. 2024 Jan 8;18(1):wrad018. doi: 10.1093/ismejo/wrad018. ISME J. 2024. PMID: 38365262 Free PMC article. No abstract available.
Full-length single-molecule protein fingerprinting.
Filius M, van Wee R, de Lannoy C, Westerlaken I, Li Z, Kim SH, de Agrela Pinto C, Wu Y, Boons GJ, Pabst M, de Ridder D, Joo C. Filius M, et al. Among authors: pabst m. Nat Nanotechnol. 2024 May;19(5):652-659. doi: 10.1038/s41565-023-01598-7. Epub 2024 Feb 13. Nat Nanotechnol. 2024. PMID: 38351230
Simple Routes to Stable Isotope-Coded Native Glycans.
Helm J, Grünwald-Gruber C, Urteil J, Pabst M, Altmann F. Helm J, et al. Among authors: pabst m. Anal Chem. 2024 Jan 9;96(1):163-169. doi: 10.1021/acs.analchem.3c03446. Epub 2023 Dec 28. Anal Chem. 2024. PMID: 38153380 Free PMC article.
305 results