Legault J - Search Results

1

Identification of an anti-inflammatory derivative with anti-cancer potential: The impact of each of its structural components on inflammatory responses in macrophages and bladder cancer cells.

Hamelin-Morrissette J, Cloutier S, Girouard J, Belgorosky D, Eiján AM, Legault J, Reyes-Moreno C, Bérubé G. Hamelin-Morrissette J, et al. Among authors: legault j. Eur J Med Chem. 2015;96:259-68. doi: 10.1016/j.ejmech.2015.04.026. Epub 2015 Apr 13. Eur J Med Chem. 2015. PMID: 25890076

2

Glycosidation of lupane-type triterpenoids as potent in vitro cytotoxic agents.

Gauthier C, Legault J, Lebrun M, Dufour P, Pichette A. Gauthier C, et al. Among authors: legault j. Bioorg Med Chem. 2006 Oct 1;14(19):6713-25. doi: 10.1016/j.bmc.2006.05.075. Epub 2006 Jun 19. Bioorg Med Chem. 2006. PMID: 16787747

3

Synthesis and structure-activity relationship study of cytotoxic germanicane- and lupane-type 3beta-O-monodesmosidic saponins starting from betulin.

Thibeault D, Gauthier C, Legault J, Bouchard J, Dufour P, Pichette A. Thibeault D, et al. Among authors: legault j. Bioorg Med Chem. 2007 Sep 15;15(18):6144-57. doi: 10.1016/j.bmc.2007.06.033. Epub 2007 Jun 20. Bioorg Med Chem. 2007. PMID: 17614290

4

Antioxidant activity, inhibition of nitric oxide overproduction, and in vitro antiproliferative effect of maple sap and syrup from Acer saccharum.

Legault J, Girard-Lalancette K, Grenon C, Dussault C, Pichette A. Legault J, et al. J Med Food. 2010 Apr;13(2):460-8. doi: 10.1089/jmf.2009.0029. J Med Food. 2010. PMID: 20132041

5

Antioxidant and anti-inflammatory activities of quercetin 7-O-β-D-glucopyranoside from the leaves of Brasenia schreberi.

Legault J, Perron T, Mshvildadze V, Girard-Lalancette K, Perron S, Laprise C, Sirois P, Pichette A. Legault J, et al. J Med Food. 2011 Oct;14(10):1127-34. doi: 10.1089/jmf.2010.0198. Epub 2011 Aug 22. J Med Food. 2011. PMID: 21859349

6

Synthesis and cytotoxicity of lupane-type triterpenoid glyceryl esters.

Thibeault D, Gauthier C, Legault J, Bouchard J, Gagné L, Pichette A. Thibeault D, et al. Among authors: legault j. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4735-9. doi: 10.1016/j.bmcl.2012.05.073. Epub 2012 May 26. Bioorg Med Chem Lett. 2012. PMID: 22704237

7

Structure elucidation of anti-methicillin resistant Staphylococcus aureus (MRSA) flavonoids from balsam poplar buds.

Simard F, Gauthier C, Legault J, Lavoie S, Mshvildadze V, Pichette A. Simard F, et al. Among authors: legault j. Bioorg Med Chem. 2016 Sep 15;24(18):4188-4198. doi: 10.1016/j.bmc.2016.07.009. Epub 2016 Jul 6. Bioorg Med Chem. 2016. PMID: 27436809

8

Antimitotic antitumor agents: synthesis, structure-activity relationships, and biological characterization of N-aryl-N'-(2-chloroethyl)ureas as new selective alkylating agents.

Mounetou E, Legault J, Lacroix J, C-Gaudreault R. Mounetou E, et al. Among authors: legault j. J Med Chem. 2001 Mar 1;44(5):694-702. doi: 10.1021/jm0010264. J Med Chem. 2001. PMID: 11262080

9

A new generation of N-aryl-N'-(1-alkyl-2-chloroethyl)ureas as microtubule disrupters: synthesis, antiproliferative activity, and beta-tubulin alkylation kinetics.

Mounetou E, Legault J, Lacroix J, C -Gaudreault R. Mounetou E, et al. Among authors: legault j. J Med Chem. 2003 Nov 6;46(23):5055-63. doi: 10.1021/jm030908a. J Med Chem. 2003. PMID: 14584955

10

Antioxidant, anti-inflammatory and anticancer activities of methanolic extracts from Ledum groenlandicum Retzius.

Dufour D, Pichette A, Mshvildadze V, Bradette-Hébert ME, Lavoie S, Longtin A, Laprise C, Legault J. Dufour D, et al. Among authors: legault j. J Ethnopharmacol. 2007 Apr 20;111(1):22-8. doi: 10.1016/j.jep.2006.10.021. Epub 2006 Oct 26. J Ethnopharmacol. 2007. PMID: 17156957

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