García-Sastre A - Search Results

1

Characterization of HIV-1 entry inhibitors with broad activity against R5 and X4 viral strains.

Sironi F, Malnati M, Mongelli N, Cozzi P, Guzzo C, Ghezzi S, Martínez-Romero C, García-Sastre A, Lusso P, Jabes D, Biswas P. Sironi F, et al. J Transl Med. 2015 Apr 2;13:107. doi: 10.1186/s12967-015-0461-9. J Transl Med. 2015. PMID: 25888743 Free PMC article.

2

An enzymatic assay for detection of viral entry.

Tscherne DM, García-Sastre A. Tscherne DM, et al. Curr Protoc Cell Biol. 2011 Jun;Chapter 26:Unit 26.12. doi: 10.1002/0471143030.cb2612s51. Curr Protoc Cell Biol. 2011. PMID: 21688257

3

Mouse dendritic cell (DC) influenza virus infectivity is much lower than that for human DCs and is hemagglutinin subtype dependent.

Hartmann BM, Li W, Jia J, Patil S, Marjanovic N, Martínez-Romero C, Albrecht RA, Hayot F, García-Sastre A, Wetmur JG, Moran TM, Sealfon SC. Hartmann BM, et al. J Virol. 2013 Feb;87(3):1916-8. doi: 10.1128/JVI.02980-12. Epub 2012 Nov 28. J Virol. 2013. PMID: 23192878 Free PMC article.

4

Substitutions T200A and E227A in the hemagglutinin of pandemic 2009 influenza A virus increase lethality but decrease transmission.

Martínez-Romero C, de Vries E, Belicha-Villanueva A, Mena I, Tscherne DM, Gillespie VL, Albrecht RA, de Haan CA, García-Sastre A. Martínez-Romero C, et al. J Virol. 2013 Jun;87(11):6507-11. doi: 10.1128/JVI.00262-13. Epub 2013 Mar 27. J Virol. 2013. PMID: 23536663 Free PMC article.

5

Evolution of the hemagglutinin protein of the new pandemic H1N1 influenza virus: maintaining optimal receptor binding by compensatory substitutions.

de Vries RP, de Vries E, Martínez-Romero C, McBride R, van Kuppeveld FJ, Rottier PJ, García-Sastre A, Paulson JC, de Haan CA. de Vries RP, et al. J Virol. 2013 Dec;87(24):13868-77. doi: 10.1128/JVI.01955-13. Epub 2013 Oct 9. J Virol. 2013. PMID: 24109242 Free PMC article.

6

ISG15 is counteracted by vaccinia virus E3 protein and controls the proinflammatory response against viral infection.

Eduardo-Correia B, Martínez-Romero C, García-Sastre A, Guerra S. Eduardo-Correia B, et al. J Virol. 2014 Feb;88(4):2312-8. doi: 10.1128/JVI.03293-13. Epub 2013 Nov 20. J Virol. 2014. PMID: 24257616 Free PMC article.

7

Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response.

Rajsbaum R, Versteeg GA, Schmid S, Maestre AM, Belicha-Villanueva A, Martínez-Romero C, Patel JR, Morrison J, Pisanelli G, Miorin L, Laurent-Rolle M, Moulton HM, Stein DA, Fernandez-Sesma A, tenOever BR, García-Sastre A. Rajsbaum R, et al. Immunity. 2014 Jun 19;40(6):880-95. doi: 10.1016/j.immuni.2014.04.018. Epub 2014 May 29. Immunity. 2014. PMID: 24882218 Free PMC article.

8

Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs.

Kouznetsova J, Sun W, Martínez-Romero C, Tawa G, Shinn P, Chen CZ, Schimmer A, Sanderson P, McKew JC, Zheng W, García-Sastre A. Kouznetsova J, et al. Emerg Microbes Infect. 2014 Dec;3(12):e84. doi: 10.1038/emi.2014.88. Epub 2014 Dec 17. Emerg Microbes Infect. 2014. PMID: 26038505 Free PMC article.

9

Against the clock towards new Ebola virus therapies.

Martínez-Romero C, García-Sastre A. Martínez-Romero C, et al. Virus Res. 2015 Nov 2;209:4-10. doi: 10.1016/j.virusres.2015.05.025. Epub 2015 Jun 6. Virus Res. 2015. PMID: 26057711 Review.

10

Antiviral Role of IFITM Proteins in African Swine Fever Virus Infection.

Muñoz-Moreno R, Cuesta-Geijo MÁ, Martínez-Romero C, Barrado-Gil L, Galindo I, García-Sastre A, Alonso C. Muñoz-Moreno R, et al. PLoS One. 2016 Apr 26;11(4):e0154366. doi: 10.1371/journal.pone.0154366. eCollection 2016. PLoS One. 2016. PMID: 27116236 Free PMC article.

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