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GWAS for executive function and processing speed suggests involvement of the CADM2 gene.
Ibrahim-Verbaas CA, Bressler J, Debette S, Schuur M, Smith AV, Bis JC, Davies G, Trompet S, Smith JA, Wolf C, Chibnik LB, Liu Y, Vitart V, Kirin M, Petrovic K, Polasek O, Zgaga L, Fawns-Ritchie C, Hoffmann P, Karjalainen J, Lahti J, Llewellyn DJ, Schmidt CO, Mather KA, Chouraki V, Sun Q, Resnick SM, Rose LM, Oldmeadow C, Stewart M, Smith BH, Gudnason V, Yang Q, Mirza SS, Jukema JW, deJager PL, Harris TB, Liewald DC, Amin N, Coker LH, Stegle O, Lopez OL, Schmidt R, Teumer A, Ford I, Karbalai N, Becker JT, Jonsdottir MK, Au R, Fehrmann R, Herms S, Nalls M, Zhao W, Turner ST, Yaffe K, Lohman K, van Swieten JC, Kardia S, Knopman DS, Meeks WM, Heiss G, Holliday EG, Schofield PW, Tanaka T, Stott DJ, Wang J, Ridker P, Gow AJ, Pattie A, Starr JM, Hocking LJ, Armstrong NJ, McLachlan S, Shulman JM, Pilling LC, Eiriksdottir G, Scott RJ, Kochan NA, Palotie A, Hsieh YC, Eriksson JG, Penman A, Gottesman RF, Oostra BA, Yu L, DeStefano AL, Beiser A, Garcia M, Rotter JI, Nöthen MM, Hofman A, Slagboom PE, Westendorp R, Buckley BM, Wolf PA, Uitterlinden AG, Psaty BM, Grabe HJ, Bandinelli S, Chasman DI, Grodstein F, Räikkönen K, Lambert JC, Porteous DJ; Generation Scotland; Price JF, Sachdev PS, Ferr… See abstract for full author list ➔ Ibrahim-Verbaas CA, et al. Among authors: cichon s. Mol Psychiatry. 2016 Feb;21(2):189-197. doi: 10.1038/mp.2015.37. Epub 2015 Apr 14. Mol Psychiatry. 2016. PMID: 25869804 Free PMC article.
A serine to glycine substitution at position 9 in the extracellular N-terminal part of the dopamine D3 receptor protein: no role in the genetic predisposition to bipolar affective disorder.
Rietschel M, Nöthen MM, Lannfelt L, Sokoloff P, Schwartz JC, Lanczik M, Fritze J, Cichon S, Fimmers R, Körner J, et al. Rietschel M, et al. Among authors: cichon s. Psychiatry Res. 1993 Mar;46(3):253-9. doi: 10.1016/0165-1781(93)90093-v. Psychiatry Res. 1993. PMID: 8493294
Systematic screening for mutations in the 5'-regulatory region of the human dopamine D1 receptor (DRD1) gene in patients with schizophrenia and bipolar affective disorder.
Cichon S, Nöthen MM, Stöber G, Schroers R, Albus M, Maier W, Rietschel M, Körner J, Weigelt B, Franzek E, Wildenauer D, Fimmers R, Propping P. Cichon S, et al. Am J Med Genet. 1996 Jul 26;67(4):424-8. doi: 10.1002/(SICI)1096-8628(19960726)67:4<424::AID-AJMG21>3.0.CO;2-K. Am J Med Genet. 1996. PMID: 8837716
564 results