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The anti-apoptotic protein HAX-1 is a regulator of cardiac function.
Zhao W, Waggoner JR, Zhang ZG, Lam CK, Han P, Qian J, Schroder PM, Mitton B, Kontrogianni-Konstantopoulos A, Robia SL, Kranias EG. Zhao W, et al. Among authors: lam ck. Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20776-81. doi: 10.1073/pnas.0906998106. Epub 2009 Nov 17. Proc Natl Acad Sci U S A. 2009. PMID: 19920172 Free PMC article.
Up-regulation of micro-RNA765 in human failing hearts is associated with post-transcriptional regulation of protein phosphatase inhibitor-1 and depressed contractility.
Cai WF, Liu GS, Lam CK, Florea S, Qian J, Zhao W, Pritchard T, Haghighi K, Lebeche D, Lu LJ, Deng J, Fan GC, Hajjar RJ, Kranias EG. Cai WF, et al. Among authors: lam ck. Eur J Heart Fail. 2015 Aug;17(8):782-93. doi: 10.1002/ejhf.323. Epub 2015 Jul 15. Eur J Heart Fail. 2015. PMID: 26177627 Free PMC article.
Human G109E-inhibitor-1 impairs cardiac function and promotes arrhythmias.
Haghighi K, Pritchard TJ, Liu GS, Singh VP, Bidwell P, Lam CK, Vafiadaki E, Das P, Ma J, Kunduri S, Sanoudou D, Florea S, Vanderbilt E, Wang HS, Rubinstein J, Hajjar RJ, Kranias EG. Haghighi K, et al. Among authors: lam ck. J Mol Cell Cardiol. 2015 Dec;89(Pt B):349-59. doi: 10.1016/j.yjmcc.2015.10.004. Epub 2015 Oct 9. J Mol Cell Cardiol. 2015. PMID: 26455482 Free PMC article.
Regulation of BECN1-mediated autophagy by HSPB6: Insights from a human HSPB6S10F mutant.
Liu GS, Zhu H, Cai WF, Wang X, Jiang M, Essandoh K, Vafiadaki E, Haghighi K, Lam CK, Gardner G, Adly G, Nicolaou P, Sanoudou D, Liang Q, Rubinstein J, Fan GC, Kranias EG. Liu GS, et al. Among authors: lam ck. Autophagy. 2018;14(1):80-97. doi: 10.1080/15548627.2017.1392420. Epub 2018 Jan 29. Autophagy. 2018. PMID: 29157081 Free PMC article.
HAX-1 regulates SERCA2a oxidation and degradation.
Bidwell PA, Liu GS, Nagarajan N, Lam CK, Haghighi K, Gardner G, Cai WF, Zhao W, Mugge L, Vafiadaki E, Sanoudou D, Rubinstein J, Lebeche D, Hajjar R, Sadoshima J, Kranias EG. Bidwell PA, et al. Among authors: lam ck. J Mol Cell Cardiol. 2018 Jan;114:220-233. doi: 10.1016/j.yjmcc.2017.11.014. Epub 2017 Nov 21. J Mol Cell Cardiol. 2018. PMID: 29169992 Free PMC article.
270 results