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Safety, tolerability, pharmacokinetics, and efficacy of AMG 403, a human anti-nerve growth factor monoclonal antibody, in two phase I studies with healthy volunteers and knee osteoarthritis subjects.
Gow JM, Tsuji WH, Williams GJ, Mytych D, Sciberras D, Searle SL, Mant T, Gibbs JP. Gow JM, et al. Among authors: mant t. Arthritis Res Ther. 2015 Oct 8;17:282. doi: 10.1186/s13075-015-0797-9. Arthritis Res Ther. 2015. PMID: 26449617 Free PMC article. Clinical Trial.
Effects of CYP3A4 Inhibitors Ketoconazole and Verapamil and the CYP3A4 Inducer Rifampicin on the Pharmacokinetic Parameters of Fostamatinib: Results from In Vitro and Phase I Clinical Studies.
Martin P, Gillen M, Millson D, Oliver S, Brealey C, Grossbard EB, Baluom M, Lau D, Sweeny D, Mant T, Craven K. Martin P, et al. Among authors: mant t. Drugs R D. 2016 Mar;16(1):81-92. doi: 10.1007/s40268-015-0118-4. Drugs R D. 2016. PMID: 26739683 Free PMC article. Clinical Trial.
Safety, tolerability and pharmacokinetics of GSK3008348, a novel integrin αvβ6 inhibitor, in healthy participants.
Maden CH, Fairman D, Chalker M, Costa MJ, Fahy WA, Garman N, Lukey PT, Mant T, Parry S, Simpson JK, Slack RJ, Kendrick S, Marshall RP. Maden CH, et al. Among authors: mant t. Eur J Clin Pharmacol. 2018 Jun;74(6):701-709. doi: 10.1007/s00228-018-2435-3. Epub 2018 Mar 12. Eur J Clin Pharmacol. 2018. PMID: 29532104 Free PMC article. Clinical Trial.
Maximum tolerated dose evaluation of the AMPA modulator Org 26576 in healthy volunteers and depressed patients: a summary and method analysis of bridging research in support of phase II dose selection.
Nations KR, Bursi R, Dogterom P, Ereshefsky L, Gertsik L, Mant T, Schipper J. Nations KR, et al. Among authors: mant t. Drugs R D. 2012 Sep 1;12(3):127-39. doi: 10.2165/11634360-000000000-00000. Drugs R D. 2012. PMID: 22852579 Free PMC article. Clinical Trial.
89 results