Lama L - Search Results

1

New insights into the promoterless transcription of DNA coligo templates by RNA polymerase III.

Lama L, Seidl CI, Ryan K. Lama L, et al. Transcription. 2014;5(2):e27913. doi: 10.4161/trns.27913. Transcription. 2014. PMID: 25764216 Free PMC article.

2

Circularized synthetic oligodeoxynucleotides serve as promoterless RNA polymerase III templates for small RNA generation in human cells.

Seidl CI, Lama L, Ryan K. Seidl CI, et al. Among authors: lama l. Nucleic Acids Res. 2013 Feb 1;41(4):2552-64. doi: 10.1093/nar/gks1334. Epub 2012 Dec 28. Nucleic Acids Res. 2013. PMID: 23275570 Free PMC article.

3

Adenylylation of small RNA sequencing adapters using the TS2126 RNA ligase I.

Lama L, Ryan K. Lama L, et al. RNA. 2016 Jan;22(1):155-61. doi: 10.1261/rna.054999.115. Epub 2015 Nov 13. RNA. 2016. PMID: 26567315 Free PMC article.

4

RNA polymerase III initiation on coligo DNA templates containing loops of variable sequence, size and nucleotide chemistry.

Patel J, Lama L, Hoffmann NA, Cobo J, Müller CW, Ryan K. Patel J, et al. Among authors: lama l. Gene. 2017 May 15;612:49-54. doi: 10.1016/j.gene.2016.09.001. Epub 2016 Sep 2. Gene. 2017. PMID: 27593562 Free PMC article.

5

Small RNA-seq: The RNA 5'-end adapter ligation problem and how to circumvent it.

Lama L, Cobo J, Buenaventura D, Ryan K. Lama L, et al. J Biol Methods. 2019;6(1):e108. doi: 10.14440/jbm.2019.269. Epub 2019 Feb 20. J Biol Methods. 2019. PMID: 31080843 Free PMC article.

6

Starting and stopping RNA polymerase III transcription on single-stranded DNA oligonucleotides.

Lama L, Ryan K. Lama L, et al. RNA. 2022 Oct;28(10):1315-1324. doi: 10.1261/rna.078981.121. Epub 2022 Jul 19. RNA. 2022. PMID: 35853667 Free PMC article.

7

Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice.

Vincent J, Adura C, Gao P, Luz A, Lama L, Asano Y, Okamoto R, Imaeda T, Aida J, Rothamel K, Gogakos T, Steinberg J, Reasoner S, Aso K, Tuschl T, Patel DJ, Glickman JF, Ascano M. Vincent J, et al. Among authors: lama l. Nat Commun. 2017 Sep 29;8(1):750. doi: 10.1038/s41467-017-00833-9. Nat Commun. 2017. PMID: 28963528 Free PMC article.

8

Publisher Correction: Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice.

Vincent J, Adura C, Gao P, Luz A, Lama L, Asano Y, Okamoto R, Imaeda T, Aida J, Rothamel K, Gogakos T, Steinberg J, Reasoner S, Aso K, Tuschl T, Patel DJ, Glickman JF, Ascano M. Vincent J, et al. Among authors: lama l. Nat Commun. 2017 Nov 23;8(1):1827. doi: 10.1038/s41467-017-01770-3. Nat Commun. 2017. PMID: 29170402 Free PMC article.

9

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression.

Lama L, Adura C, Xie W, Tomita D, Kamei T, Kuryavyi V, Gogakos T, Steinberg JI, Miller M, Ramos-Espiritu L, Asano Y, Hashizume S, Aida J, Imaeda T, Okamoto R, Jennings AJ, Michino M, Kuroita T, Stamford A, Gao P, Meinke P, Glickman JF, Patel DJ, Tuschl T. Lama L, et al. Nat Commun. 2019 May 21;10(1):2261. doi: 10.1038/s41467-019-08620-4. Nat Commun. 2019. PMID: 31113940 Free PMC article.

10

Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation.

Xie W, Lama L, Adura C, Tomita D, Glickman JF, Tuschl T, Patel DJ. Xie W, et al. Among authors: lama l. Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11946-11955. doi: 10.1073/pnas.1905013116. Epub 2019 May 29. Proc Natl Acad Sci U S A. 2019. PMID: 31142647 Free PMC article.

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