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Oral lipid-based nanoformulation of tafenoquine enhanced bioavailability and blood stage antimalarial efficacy and led to a reduction in human red blood cell loss in mice.
Melariri P, Kalombo L, Nkuna P, Dube A, Hayeshi R, Ogutu B, Gibhard L, deKock C, Smith P, Wiesner L, Swai H. Melariri P, et al. Among authors: ogutu b. Int J Nanomedicine. 2015 Feb 20;10:1493-503. doi: 10.2147/IJN.S76317. eCollection 2015. Int J Nanomedicine. 2015. PMID: 25759576 Free PMC article.
Impact of parasite genomic dynamics on the sensitivity of Plasmodium falciparum isolates to piperaquine and other antimalarial drugs.
Wakoli DM, Ondigo BN, Ochora DO, Amwoma JG, Okore W, Mwakio EW, Chemwor G, Juma J, Okoth R, Okudo C, Yeda R, Opot BH, Cheruiyot AC, Juma D, Roth A, Ogutu BR, Boudreaux D, Andagalu B, Akala HM. Wakoli DM, et al. Among authors: ogutu br. BMC Med. 2022 Nov 18;20(1):448. doi: 10.1186/s12916-022-02652-2. BMC Med. 2022. PMID: 36397090 Free PMC article.
Ganaplacide (KAF156) plus lumefantrine solid dispersion formulation combination for uncomplicated Plasmodium falciparum malaria: an open-label, multicentre, parallel-group, randomised, controlled, phase 2 trial.
Ogutu B, Yeka A, Kusemererwa S, Thompson R, Tinto H, Toure AO, Uthaisin C, Verma A, Kibuuka A, Lingani M, Lourenço C, Mombo-Ngoma G, Nduba V, N'Guessan TL, Nassa GJW, Nyantaro M, Tina LO, Singh PK, El Gaaloul M, Marrast AC, Chikoto H, Csermak K, Demin I, Mehta D, Pathan R, Risterucci C, Su G, Winnips C, Kaguthi G, Fofana B, Grobusch MP. Ogutu B, et al. Lancet Infect Dis. 2023 Sep;23(9):1051-1061. doi: 10.1016/S1473-3099(23)00209-8. Epub 2023 Jun 13. Lancet Infect Dis. 2023. PMID: 37327809 Clinical Trial.
Variability in white blood cell count during uncomplicated malaria and implications for parasite density estimation: a WorldWide Antimalarial Resistance Network individual patient data meta-analysis.
WorldWide Antimalarial Resistance Network White Blood Cell Count in Malaria Study Group. WorldWide Antimalarial Resistance Network White Blood Cell Count in Malaria Study Group. Malar J. 2023 Jun 6;22(1):174. doi: 10.1186/s12936-023-04583-6. Malar J. 2023. PMID: 37280686 Free PMC article.
Characterization of a novel Plasmodium falciparum merozoite surface antigen and potential vaccine target.
Niaré K, Chege T, Rosenkranz M, Mwai K, Saßmannshausen Z, Odera D, Nyamako L, Tuju J, Alfred T, Waitumbi JN, Ogutu B, Sirima SB, Awandare G, Kouriba B, Rayner JC, Osier FHA. Niaré K, et al. Among authors: ogutu b. Front Immunol. 2023 Apr 14;14:1156806. doi: 10.3389/fimmu.2023.1156806. eCollection 2023. Front Immunol. 2023. PMID: 37122725 Free PMC article.
208 results