McLeod SM - Search Results

1

Novel antibacterial targets and compounds revealed by a high-throughput cell wall reporter assay.

Nayar AS, Dougherty TJ, Ferguson KE, Granger BA, McWilliams L, Stacey C, Leach LJ, Narita S, Tokuda H, Miller AA, Brown DG, McLeod SM. Nayar AS, et al. Among authors: mcleod sm. J Bacteriol. 2015 May;197(10):1726-34. doi: 10.1128/JB.02552-14. Epub 2015 Mar 2. J Bacteriol. 2015. PMID: 25733621 Free PMC article.

2

Small-molecule inhibitors of gram-negative lipoprotein trafficking discovered by phenotypic screening.

McLeod SM, Fleming PR, MacCormack K, McLaughlin RE, Whiteaker JD, Narita S, Mori M, Tokuda H, Miller AA. McLeod SM, et al. J Bacteriol. 2015 Mar;197(6):1075-82. doi: 10.1128/JB.02352-14. Epub 2015 Jan 12. J Bacteriol. 2015. PMID: 25583975 Free PMC article.

3

Target-based whole-cell screening by ¹H NMR spectroscopy.

Ma J, Cao Q, McLeod SM, Ferguson K, Gao N, Breeze AL, Hu J. Ma J, et al. Among authors: mcleod sm. Angew Chem Int Ed Engl. 2015 Apr 13;54(16):4764-7. doi: 10.1002/anie.201410701. Epub 2015 Feb 18. Angew Chem Int Ed Engl. 2015. PMID: 25693499 Free PMC article.

4

Frequency and Mechanism of Spontaneous Resistance to Sulbactam Combined with the Novel β-Lactamase Inhibitor ETX2514 in Clinical Isolates of Acinetobacter baumannii.

McLeod SM, Shapiro AB, Moussa SH, Johnstone M, McLaughlin RE, de Jonge BLM, Miller AA. McLeod SM, et al. Antimicrob Agents Chemother. 2018 Jan 25;62(2):e01576-17. doi: 10.1128/AAC.01576-17. Print 2018 Feb. Antimicrob Agents Chemother. 2018. PMID: 29133555 Free PMC article.

5

In Vitro Activity of Sulbactam-Durlobactam against Acinetobacter baumannii-calcoaceticus Complex Isolates Collected Globally in 2016 and 2017.

McLeod SM, Moussa SH, Hackel MA, Miller AA. McLeod SM, et al. Antimicrob Agents Chemother. 2020 Mar 24;64(4):e02534-19. doi: 10.1128/AAC.02534-19. Print 2020 Mar 24. Antimicrob Agents Chemother. 2020. PMID: 31988095 Free PMC article.

6

In Vitro Characterization of ETX1317, a Broad-Spectrum β-Lactamase Inhibitor That Restores and Enhances β-Lactam Activity against Multi-Drug-Resistant Enterobacteriales, Including Carbapenem-Resistant Strains.

Miller AA, Shapiro AB, McLeod SM, Carter NM, Moussa SH, Tommasi R, Mueller JP. Miller AA, et al. Among authors: mcleod sm. ACS Infect Dis. 2020 Jun 12;6(6):1389-1397. doi: 10.1021/acsinfecdis.0c00020. Epub 2020 May 14. ACS Infect Dis. 2020. PMID: 32255609 Free article.

7

Durlobactam, a New Diazabicyclooctane β-Lactamase Inhibitor for the Treatment of Acinetobacter Infections in Combination With Sulbactam.

Shapiro AB, Moussa SH, McLeod SM, Durand-Réville T, Miller AA. Shapiro AB, et al. Among authors: mcleod sm. Front Microbiol. 2021 Jul 19;12:709974. doi: 10.3389/fmicb.2021.709974. eCollection 2021. Front Microbiol. 2021. PMID: 34349751 Free PMC article. Review.

8

Discovery of an Orally Available Diazabicyclooctane Inhibitor (ETX0282) of Class A, C, and D Serine β-Lactamases.

Durand-Réville TF, Comita-Prevoir J, Zhang J, Wu X, May-Dracka TL, Romero JAC, Wu F, Chen A, Shapiro AB, Carter NM, McLeod SM, Giacobbe RA, Verheijen JC, Lahiri SD, Sacco MD, Chen Y, O'Donnell JP, Miller AA, Mueller JP, Tommasi RA. Durand-Réville TF, et al. Among authors: mcleod sm. J Med Chem. 2020 Nov 12;63(21):12511-12525. doi: 10.1021/acs.jmedchem.0c00579. Epub 2020 Jul 24. J Med Chem. 2020. PMID: 32658473 Free PMC article.

9

In Vitro Activity of Sulbactam-Durlobactam against Global Isolates of Acinetobacter baumannii-calcoaceticus Complex Collected from 2016 to 2021.

Karlowsky JA, Hackel MA, McLeod SM, Miller AA. Karlowsky JA, et al. Among authors: mcleod sm. Antimicrob Agents Chemother. 2022 Sep 20;66(9):e0078122. doi: 10.1128/aac.00781-22. Epub 2022 Aug 25. Antimicrob Agents Chemother. 2022. PMID: 36005804 Free PMC article.

10

ETX2514 is a broad-spectrum β-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii.

Durand-Réville TF, Guler S, Comita-Prevoir J, Chen B, Bifulco N, Huynh H, Lahiri S, Shapiro AB, McLeod SM, Carter NM, Moussa SH, Velez-Vega C, Olivier NB, McLaughlin R, Gao N, Thresher J, Palmer T, Andrews B, Giacobbe RA, Newman JV, Ehmann DE, de Jonge B, O'Donnell J, Mueller JP, Tommasi RA, Miller AA. Durand-Réville TF, et al. Among authors: mcleod sm. Nat Microbiol. 2017 Jun 30;2:17104. doi: 10.1038/nmicrobiol.2017.104. Nat Microbiol. 2017. PMID: 28665414

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