Pharmacological and behavioural effects of tryptamines present in psilocybin-containing mushrooms.
Rakoczy RJ, Runge GN, Sen AK, Sandoval O, Wells HG, Nguyen Q, Roberts BR, Sciortino JH, Gibbons WJ Jr, Friedberg LM, Jones JA, McMurray MS.
Rakoczy RJ, et al.
Br J Pharmacol. 2024 Jun 2. doi: 10.1111/bph.16466. Online ahead of print.
Br J Pharmacol. 2024.
PMID: 38825326
KEY RESULTS: In vitro enzyme kinetics assays found that all compounds had nearly identical rates of dephosphorylation via alkaline phosphatase and metabolism by monoamine oxidase. Further, we found that only the dephosphorylated products of baeocystin and norbaeocys …
KEY RESULTS: In vitro enzyme kinetics assays found that all compounds had nearly identical rates of dephosphorylation via alkaline phosphata …