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Bulbispermine: a crinine-type Amaryllidaceae alkaloid exhibiting cytostatic activity toward apoptosis-resistant glioma cells.
Luchetti G, Johnston R, Mathieu V, Lefranc F, Hayden K, Andolfi A, Lamoral-Theys D, Reisenauer MR, Champion C, Pelly SC, van Otterlo WA, Magedov IV, Kiss R, Evidente A, Rogelj S, Kornienko A. Luchetti G, et al. Among authors: rogelj s. ChemMedChem. 2012 May;7(5):815-22. doi: 10.1002/cmdc.201100608. Epub 2012 Mar 2. ChemMedChem. 2012. PMID: 22389235 Free PMC article.
Activity of 2-aryl-2-(3-indolyl)acetohydroxamates against drug-resistant cancer cells.
Aksenov AV, Smirnov AN, Magedov IV, Reisenauer MR, Aksenov NA, Aksenova IV, Pendleton AL, Nguyen G, Johnston RK, Rubin M, De Carvalho A, Kiss R, Mathieu V, Lefranc F, Correa J, Cavazos DA, Brenner AJ, Bryan BA, Rogelj S, Kornienko A, Frolova LV. Aksenov AV, et al. Among authors: rogelj s. J Med Chem. 2015 Mar 12;58(5):2206-20. doi: 10.1021/jm501518y. Epub 2015 Feb 20. J Med Chem. 2015. PMID: 25671501 Free PMC article.
Exploring natural product chemistry and biology with multicomponent reactions. 5. Discovery of a novel tubulin-targeting scaffold derived from the rigidin family of marine alkaloids.
Frolova LV, Magedov IV, Romero AE, Karki M, Otero I, Hayden K, Evdokimov NM, Banuls LM, Rastogi SK, Smith WR, Lu SL, Kiss R, Shuster CB, Hamel E, Betancourt T, Rogelj S, Kornienko A. Frolova LV, et al. Among authors: rogelj s. J Med Chem. 2013 Sep 12;56(17):6886-900. doi: 10.1021/jm400711t. Epub 2013 Aug 23. J Med Chem. 2013. PMID: 23927793 Free PMC article.
Spectroscopic Study of a Photoactive Antibacterial Agent: 2,3-Distyrylindole.
Rajapaksha RD, Banet M, Champion C, Frolova LV, Rogelj S, Choudhury P, Ranasinghe MI. Rajapaksha RD, et al. Among authors: rogelj s. J Phys Chem A. 2018 Feb 1;122(4):937-945. doi: 10.1021/acs.jpca.7b09638. Epub 2018 Jan 23. J Phys Chem A. 2018. PMID: 29303582 Free PMC article.
Structural simplification of bioactive natural products with multicomponent synthesis. 2. antiproliferative and antitubulin activities of pyrano[3,2-c]pyridones and pyrano[3,2-c]quinolones.
Magedov IV, Manpadi M, Ogasawara MA, Dhawan AS, Rogelj S, Van Slambrouck S, Steelant WF, Evdokimov NM, Uglinskii PY, Elias EM, Knee EJ, Tongwa P, Antipin MY, Kornienko A. Magedov IV, et al. Among authors: rogelj s. J Med Chem. 2008 Apr 24;51(8):2561-70. doi: 10.1021/jm701499n. Epub 2008 Mar 25. J Med Chem. 2008. PMID: 18361483 Free PMC article.
Structural simplification of bioactive natural products with multicomponent synthesis. 3. Fused uracil-containing heterocycles as novel topoisomerase-targeting agents.
Evdokimov NM, Van Slambrouck S, Heffeter P, Tu L, Le Calvé B, Lamoral-Theys D, Hooten CJ, Uglinskii PY, Rogelj S, Kiss R, Steelant WF, Berger W, Yang JJ, Bologa CG, Kornienko A, Magedov IV. Evdokimov NM, et al. Among authors: rogelj s. J Med Chem. 2011 Apr 14;54(7):2012-21. doi: 10.1021/jm1009428. Epub 2011 Mar 9. J Med Chem. 2011. PMID: 21388138 Free PMC article.
70 results