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Early emergence of T central memory precursors programs clonal dominance during chronic viral infection.
Grassmann S, Mihatsch L, Mir J, Kazeroonian A, Rahimi R, Flommersfeld S, Schober K, Hensel I, Leube J, Pachmayr LO, Kretschmer L, Zhang Q, Jolly A, Chaudhry MZ, Schiemann M, Cicin-Sain L, Höfer T, Busch DH, Flossdorf M, Buchholz VR. Grassmann S, et al. Among authors: flossdorf m. Nat Immunol. 2020 Dec;21(12):1563-1573. doi: 10.1038/s41590-020-00807-y. Epub 2020 Oct 26. Nat Immunol. 2020. PMID: 33106669
The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes.
Stittrich AB, Haftmann C, Sgouroudis E, Kühl AA, Hegazy AN, Panse I, Riedel R, Flossdorf M, Dong J, Fuhrmann F, Heinz GA, Fang Z, Li N, Bissels U, Hatam F, Jahn A, Hammoud B, Matz M, Schulze FM, Baumgrass R, Bosio A, Mollenkopf HJ, Grün J, Thiel A, Chen W, Höfer T, Loddenkemper C, Löhning M, Chang HD, Rajewsky N, Radbruch A, Mashreghi MF. Stittrich AB, et al. Among authors: flossdorf m. Nat Immunol. 2010 Nov;11(11):1057-62. doi: 10.1038/ni.1945. Epub 2010 Oct 10. Nat Immunol. 2010. PMID: 20935646
Disparate individual fates compose robust CD8+ T cell immunity.
Buchholz VR, Flossdorf M, Hensel I, Kretschmer L, Weissbrich B, Gräf P, Verschoor A, Schiemann M, Höfer T, Busch DH. Buchholz VR, et al. Among authors: flossdorf m. Science. 2013 May 3;340(6132):630-5. doi: 10.1126/science.1235454. Epub 2013 Mar 14. Science. 2013. PMID: 23493420
Individual T helper cells have a quantitative cytokine memory.
Helmstetter C, Flossdorf M, Peine M, Kupz A, Zhu J, Hegazy AN, Duque-Correa MA, Zhang Q, Vainshtein Y, Radbruch A, Kaufmann SH, Paul WE, Höfer T, Löhning M. Helmstetter C, et al. Among authors: flossdorf m. Immunity. 2015 Jan 20;42(1):108-22. doi: 10.1016/j.immuni.2014.12.018. Epub 2014 Dec 25. Immunity. 2015. PMID: 25607461 Free PMC article.
26 results