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Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma.
Shakhova O, Cheng P, Mishra PJ, Zingg D, Schaefer SM, Debbache J, Häusel J, Matter C, Guo T, Davis S, Meltzer P, Mihic-Probst D, Moch H, Wegner M, Merlino G, Levesque MP, Dummer R, Santoro R, Cinelli P, Sommer L. Shakhova O, et al. PLoS Genet. 2015 Jan 28;11(1):e1004877. doi: 10.1371/journal.pgen.1004877. eCollection 2015 Jan. PLoS Genet. 2015. PMID: 25629959 Free PMC article.
Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma.
Shakhova O, Zingg D, Schaefer SM, Hari L, Civenni G, Blunschi J, Claudinot S, Okoniewski M, Beermann F, Mihic-Probst D, Moch H, Wegner M, Dummer R, Barrandon Y, Cinelli P, Sommer L. Shakhova O, et al. Nat Cell Biol. 2012 Aug;14(8):882-90. doi: 10.1038/ncb2535. Epub 2012 Jul 8. Nat Cell Biol. 2012. PMID: 22772081 Free article.
The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors.
Zingg D, Debbache J, Schaefer SM, Tuncer E, Frommel SC, Cheng P, Arenas-Ramirez N, Haeusel J, Zhang Y, Bonalli M, McCabe MT, Creasy CL, Levesque MP, Boyman O, Santoro R, Shakhova O, Dummer R, Sommer L. Zingg D, et al. Among authors: shakhova o. Nat Commun. 2015 Jan 22;6:6051. doi: 10.1038/ncomms7051. Nat Commun. 2015. PMID: 25609585 Free article.
Methylation-dependent SOX9 expression mediates invasion in human melanoma cells and is a negative prognostic factor in advanced melanoma.
Cheng PF, Shakhova O, Widmer DS, Eichhoff OM, Zingg D, Frommel SC, Belloni B, Raaijmakers MI, Goldinger SM, Santoro R, Hemmi S, Sommer L, Dummer R, Levesque MP. Cheng PF, et al. Among authors: shakhova o. Genome Biol. 2015 Feb 22;16(1):42. doi: 10.1186/s13059-015-0594-4. Genome Biol. 2015. PMID: 25885555 Free PMC article.
Injury-activated glial cells promote wound healing of the adult skin in mice.
Parfejevs V, Debbache J, Shakhova O, Schaefer SM, Glausch M, Wegner M, Suter U, Riekstina U, Werner S, Sommer L. Parfejevs V, et al. Among authors: shakhova o. Nat Commun. 2018 Jan 16;9(1):236. doi: 10.1038/s41467-017-01488-2. Nat Commun. 2018. PMID: 29339718 Free PMC article.
An Aggressive Hypoxia Related Subpopulation of Melanoma Cells is TRP-2 Negative.
Lenggenhager D, Curioni-Fontecedro A, Storz M, Shakhova O, Sommer L, Widmer DS, Seifert B, Moch H, Dummer R, Mihic-Probst D. Lenggenhager D, et al. Among authors: shakhova o. Transl Oncol. 2014 Apr;7(2):206-12. doi: 10.1016/j.tranon.2014.02.018. Epub 2014 Apr 17. Transl Oncol. 2014. PMID: 24746711 Free PMC article.
39 results