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Unbiased screening of marine sponge extracts for anti-inflammatory agents combined with chemical genomics identifies girolline as an inhibitor of protein synthesis.
Fung SY, Sofiyev V, Schneiderman J, Hirschfeld AF, Victor RE, Woods K, Piotrowski JS, Deshpande R, Li SC, de Voogd NJ, Myers CL, Boone C, Andersen RJ, Turvey SE. Fung SY, et al. Among authors: andersen rj. ACS Chem Biol. 2014 Jan 17;9(1):247-57. doi: 10.1021/cb400740c. Epub 2013 Oct 29. ACS Chem Biol. 2014. PMID: 24117378 Free PMC article.
Clionamines stimulate autophagy, inhibit Mycobacterium tuberculosis survival in macrophages, and target Pik1.
Persaud R, Li SC, Chao JD, Forestieri R, Donohue E, Balgi AD, Zheng X, Chao JT, Yashiroda Y, Yoshimura M, Loewen CJR, Gingras AC, Boone C, Av-Gay Y, Roberge M, Andersen RJ. Persaud R, et al. Among authors: andersen rj. Cell Chem Biol. 2022 May 19;29(5):870-882.e11. doi: 10.1016/j.chembiol.2021.07.017. Epub 2021 Sep 13. Cell Chem Biol. 2022. PMID: 34520745 Free article.
Exploring the mode-of-action of bioactive compounds by chemical-genetic profiling in yeast.
Parsons AB, Lopez A, Givoni IE, Williams DE, Gray CA, Porter J, Chua G, Sopko R, Brost RL, Ho CH, Wang J, Ketela T, Brenner C, Brill JA, Fernandez GE, Lorenz TC, Payne GS, Ishihara S, Ohya Y, Andrews B, Hughes TR, Frey BJ, Graham TR, Andersen RJ, Boone C. Parsons AB, et al. Among authors: andersen rj. Cell. 2006 Aug 11;126(3):611-25. doi: 10.1016/j.cell.2006.06.040. Cell. 2006. PMID: 16901791 Free article.
A molecular barcoded yeast ORF library enables mode-of-action analysis of bioactive compounds.
Ho CH, Magtanong L, Barker SL, Gresham D, Nishimura S, Natarajan P, Koh JLY, Porter J, Gray CA, Andersen RJ, Giaever G, Nislow C, Andrews B, Botstein D, Graham TR, Yoshida M, Boone C. Ho CH, et al. Among authors: andersen rj. Nat Biotechnol. 2009 Apr;27(4):369-77. doi: 10.1038/nbt.1534. Epub 2009 Apr 6. Nat Biotechnol. 2009. PMID: 19349972 Free PMC article.
274 results