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Decatransin, a new natural product inhibiting protein translocation at the Sec61/SecYEG translocon.
Junne T, Wong J, Studer C, Aust T, Bauer BW, Beibel M, Bhullar B, Bruccoleri R, Eichenberger J, Estoppey D, Hartmann N, Knapp B, Krastel P, Melin N, Oakeley EJ, Oberer L, Riedl R, Roma G, Schuierer S, Petersen F, Tallarico JA, Rapoport TA, Spiess M, Hoepfner D. Junne T, et al. Among authors: hartmann n. J Cell Sci. 2015 Mar 15;128(6):1217-29. doi: 10.1242/jcs.165746. Epub 2015 Jan 22. J Cell Sci. 2015. PMID: 25616894 Free PMC article.
High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions.
Hoepfner D, Helliwell SB, Sadlish H, Schuierer S, Filipuzzi I, Brachat S, Bhullar B, Plikat U, Abraham Y, Altorfer M, Aust T, Baeriswyl L, Cerino R, Chang L, Estoppey D, Eichenberger J, Frederiksen M, Hartmann N, Hohendahl A, Knapp B, Krastel P, Melin N, Nigsch F, Oakeley EJ, Petitjean V, Petersen F, Riedl R, Schmitt EK, Staedtler F, Studer C, Tallarico JA, Wetzel S, Fishman MC, Porter JA, Movva NR. Hoepfner D, et al. Among authors: hartmann n. Microbiol Res. 2014 Feb-Mar;169(2-3):107-20. doi: 10.1016/j.micres.2013.11.004. Epub 2013 Dec 1. Microbiol Res. 2014. PMID: 24360837 Free article.
Selective and specific inhibition of the plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin.
Hoepfner D, McNamara CW, Lim CS, Studer C, Riedl R, Aust T, McCormack SL, Plouffe DM, Meister S, Schuierer S, Plikat U, Hartmann N, Staedtler F, Cotesta S, Schmitt EK, Petersen F, Supek F, Glynne RJ, Tallarico JA, Porter JA, Fishman MC, Bodenreider C, Diagana TT, Movva NR, Winzeler EA. Hoepfner D, et al. Among authors: hartmann n. Cell Host Microbe. 2012 Jun 14;11(6):654-63. doi: 10.1016/j.chom.2012.04.015. Cell Host Microbe. 2012. PMID: 22704625 Free PMC article.
Identification and evaluation of novel acetolactate synthase inhibitors as antifungal agents.
Richie DL, Thompson KV, Studer C, Prindle VC, Aust T, Riedl R, Estoppey D, Tao J, Sexton JA, Zabawa T, Drumm J, Cotesta S, Eichenberger J, Schuierer S, Hartmann N, Movva NR, Tallarico JA, Ryder NS, Hoepfner D. Richie DL, et al. Among authors: hartmann n. Antimicrob Agents Chemother. 2013 May;57(5):2272-80. doi: 10.1128/AAC.01809-12. Epub 2013 Mar 11. Antimicrob Agents Chemother. 2013. PMID: 23478965 Free PMC article.
Robust and tissue-independent gender-specific transcript biomarkers.
Staedtler F, Hartmann N, Letzkus M, Bongiovanni S, Scherer A, Marc P, Johnson KJ, Schumacher MM. Staedtler F, et al. Among authors: hartmann n. Biomarkers. 2013 Aug;18(5):436-45. doi: 10.3109/1354750X.2013.811538. Epub 2013 Jul 8. Biomarkers. 2013. PMID: 23829492
Transcriptome changes in renal allograft protocol biopsies at 3 months precede the onset of interstitial fibrosis/tubular atrophy (IF/TA) at 6 months.
Scherer A, Gwinner W, Mengel M, Kirsch T, Raulf F, Szustakowski JD, Hartmann N, Staedtler F, Engel G, Klupp J, Korn A, Kehren J, Haller H. Scherer A, et al. Among authors: hartmann n. Nephrol Dial Transplant. 2009 Aug;24(8):2567-75. doi: 10.1093/ndt/gfp183. Epub 2009 Apr 27. Nephrol Dial Transplant. 2009. PMID: 19398767
513 results