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microRNA-379 couples glucocorticoid hormones to dysfunctional lipid homeostasis.
de Guia RM, Rose AJ, Sommerfeld A, Seibert O, Strzoda D, Zota A, Feuchter Y, Krones-Herzig A, Sijmonsma T, Kirilov M, Sticht C, Gretz N, Dallinga-Thie G, Diederichs S, Klöting N, Blüher M, Berriel Diaz M, Herzig S. de Guia RM, et al. EMBO J. 2015 Feb 3;34(3):344-60. doi: 10.15252/embj.201490464. Epub 2014 Dec 15. EMBO J. 2015. PMID: 25510864 Free PMC article. Clinical Trial.
TSC22D4 is a molecular output of hepatic wasting metabolism.
Jones A, Friedrich K, Rohm M, Schäfer M, Algire C, Kulozik P, Seibert O, Müller-Decker K, Sijmonsma T, Strzoda D, Sticht C, Gretz N, Dallinga-Thie GM, Leuchs B, Kögl M, Stremmel W, Diaz MB, Herzig S. Jones A, et al. EMBO Mol Med. 2013 Feb;5(2):294-308. doi: 10.1002/emmm.201201869. Epub 2013 Jan 11. EMBO Mol Med. 2013. PMID: 23307490 Free PMC article.
Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia.
Kulozik P, Jones A, Mattijssen F, Rose AJ, Reimann A, Strzoda D, Kleinsorg S, Raupp C, Kleinschmidt J, Müller-Decker K, Wahli W, Sticht C, Gretz N, von Loeffelholz C, Stockmann M, Pfeiffer A, Stöhr S, Dallinga-Thie GM, Nawroth PP, Diaz MB, Herzig S. Kulozik P, et al. Cell Metab. 2011 Apr 6;13(4):389-400. doi: 10.1016/j.cmet.2011.02.011. Cell Metab. 2011. PMID: 21459324 Free article.
Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions.
Hoeksema MA, Gijbels MJ, Van den Bossche J, van der Velden S, Sijm A, Neele AE, Seijkens T, Stöger JL, Meiler S, Boshuizen MC, Dallinga-Thie GM, Levels JH, Boon L, Mullican SE, Spann NJ, Cleutjens JP, Glass CK, Lazar MA, de Vries CJ, Biessen EA, Daemen MJ, Lutgens E, de Winther MP. Hoeksema MA, et al. EMBO Mol Med. 2014 Sep;6(9):1124-32. doi: 10.15252/emmm.201404170. EMBO Mol Med. 2014. PMID: 25007801 Free PMC article.
Lactate increases hepatic secretion of VLDL-triglycerides in humans.
Sondermeijer BM, Battjes S, van Dijk TH, Ackermans MT, Serlie MJ, Nieuwdorp M, Groen AK, Dallinga-Thie GM, Stroes ES. Sondermeijer BM, et al. Atherosclerosis. 2013 Jun;228(2):443-50. doi: 10.1016/j.atherosclerosis.2013.02.040. Epub 2013 Mar 14. Atherosclerosis. 2013. PMID: 23540683 Free article. Clinical Trial.
Pathophysiology of hypertriglyceridemia.
Hassing HC, Surendran RP, Mooij HL, Stroes ES, Nieuwdorp M, Dallinga-Thie GM. Hassing HC, et al. Biochim Biophys Acta. 2012 May;1821(5):826-32. doi: 10.1016/j.bbalip.2011.11.010. Epub 2011 Dec 10. Biochim Biophys Acta. 2012. PMID: 22179026 Review.
240 results