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Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity-implications for therapeutic targeting of Nrf2.
Free Radic Biol Med. 2015 Jan;78:202-12. doi: 10.1016/j.freeradbiomed.2014.11.003. Epub 2014 Nov 14.
Free Radic Biol Med. 2015.
PMID: 25445704
Free PMC article.
Failure to upregulate cell surface PD-1 is associated with dysregulated stimulation of T cells by TGN1412-like CD28 superagonist.
Thaventhiran T, Alhumeed N, Yeang HX, Sethu S, Downey JS, Alghanem AF, Olayanju A, Smith EL, Cross MJ, Webb SD, Williams DP, Bristow A, Ball C, Stebbings R, Sathish JG.
Thaventhiran T, et al. Among authors: alghanem af.
MAbs. 2014;6(5):1290-9. doi: 10.4161/mabs.29758. Epub 2014 Oct 30.
MAbs. 2014.
PMID: 25517314
Free PMC article.
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RCAN1.4 regulates VEGFR-2 internalisation, cell polarity and migration in human microvascular endothelial cells.
Alghanem AF, Wilkinson EL, Emmett MS, Aljasir MA, Holmes K, Rothermel BA, Simms VA, Heath VL, Cross MJ.
Alghanem AF, et al.
Angiogenesis. 2017 Aug;20(3):341-358. doi: 10.1007/s10456-017-9542-0. Epub 2017 Mar 7.
Angiogenesis. 2017.
PMID: 28271280
Free PMC article.
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CD28 Superagonistic Activation of T Cells Induces a Tumor Cell-Like Metabolic Program.
Thaventhiran T, Wong W, Alghanem AF, Alhumeed N, Aljasir MA, Ramsey S, Sethu S, Yeang HXA, Chadwick AE, Cross M, Webb SD, Djouhri L, Ball C, Stebbings R, Sathish JG.
Thaventhiran T, et al. Among authors: alghanem af.
Monoclon Antib Immunodiagn Immunother. 2019 Apr;38(2):60-69. doi: 10.1089/mab.2018.0042.
Monoclon Antib Immunodiagn Immunother. 2019.
PMID: 31009338
Free PMC article.
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The SWELL1-LRRC8 complex regulates endothelial AKT-eNOS signaling and vascular function.
Alghanem AF, Abello J, Maurer JM, Kumar A, Ta CM, Gunasekar SK, Fatima U, Kang C, Xie L, Adeola O, Riker M, Elliot-Hudson M, Minerath RA, Grueter CE, Mullins RF, Stratman AN, Sah R.
Alghanem AF, et al.
Elife. 2021 Feb 25;10:e61313. doi: 10.7554/eLife.61313.
Elife. 2021.
PMID: 33629656
Free PMC article.
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Metabolic Syndrome, Dyslipidemia and Regulation of Lipoprotein Metabolism.
Iqbal J, Al Qarni A, Hawwari A, Alghanem AF, Ahmed G.
Iqbal J, et al. Among authors: alghanem af.
Curr Diabetes Rev. 2018;14(5):427-433. doi: 10.2174/1573399813666170705161039.
Curr Diabetes Rev. 2018.
PMID: 28677496
Review.
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Systematic Transmission Electron Microscopy-Based Identification and 3D Reconstruction of Cellular Degradation Machinery.
Neikirk K, Vue Z, Katti P, Rodriguez BI, Omer S, Shao J, Christensen T, Garza Lopez E, Marshall A, Palavicino-Maggio CB, Ponce J, Alghanem AF, Vang L, Barongan T, Beasley HK, Rodman T, Stephens D, Mungai M, Correia M, Exil V, Damo S, Murray SA, Crabtree A, Glancy B, Pereira RO, Abel ED, Hinton AO Jr.
Neikirk K, et al. Among authors: alghanem af.
Adv Biol (Weinh). 2023 Jun;7(6):e2200221. doi: 10.1002/adbi.202200221. Epub 2023 Mar 3.
Adv Biol (Weinh). 2023.
PMID: 36869426
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Impact of empirical oseltamivir discontinuation in hospitalized patients with community-acquired pneumonia after confirmed negative for influenza.
Alghanem AF, Aldhahri FA, Althemery AU.
Alghanem AF, et al.
Saudi Med J. 2021 Oct;42(10):1072-1077. doi: 10.15537/smj.2021.42.10.20210324.
Saudi Med J. 2021.
PMID: 34611001
Free PMC article.
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