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Merging pathology with biomechanics using CHIMERA (Closed-Head Impact Model of Engineered Rotational Acceleration): a novel, surgery-free model of traumatic brain injury.
Namjoshi DR, Cheng WH, McInnes KA, Martens KM, Carr M, Wilkinson A, Fan J, Robert J, Hayat A, Cripton PA, Wellington CL. Namjoshi DR, et al. Among authors: martens km. Mol Neurodegener. 2014 Dec 1;9:55. doi: 10.1186/1750-1326-9-55. Mol Neurodegener. 2014. PMID: 25443413 Free PMC article.
CHIMERA repetitive mild traumatic brain injury induces chronic behavioural and neuropathological phenotypes in wild-type and APP/PS1 mice.
Cheng WH, Martens KM, Bashir A, Cheung H, Stukas S, Gibbs E, Namjoshi DR, Button EB, Wilkinson A, Barron CJ, Cashman NR, Cripton PA, Wellington CL. Cheng WH, et al. Among authors: martens km. Alzheimers Res Ther. 2019 Jan 12;11(1):6. doi: 10.1186/s13195-018-0461-0. Alzheimers Res Ther. 2019. PMID: 30636629 Free PMC article.
Repetitive closed-head impact model of engineered rotational acceleration (CHIMERA) injury in rats increases impulsivity, decreases dopaminergic innervation in the olfactory tubercle and generates white matter inflammation, tau phosphorylation and degeneration.
Vonder Haar C, Martens KM, Bashir A, McInnes KA, Cheng WH, Cheung H, Stukas S, Barron C, Ladner T, Welch KA, Cripton PA, Winstanley CA, Wellington CL. Vonder Haar C, et al. Among authors: martens km. Exp Neurol. 2019 Jul;317:87-99. doi: 10.1016/j.expneurol.2019.02.012. Epub 2019 Feb 26. Exp Neurol. 2019. PMID: 30822421
Defining the biomechanical and biological threshold of murine mild traumatic brain injury using CHIMERA (Closed Head Impact Model of Engineered Rotational Acceleration).
Namjoshi DR, Cheng WH, Bashir A, Wilkinson A, Stukas S, Martens KM, Whyte T, Abebe ZA, McInnes KA, Cripton PA, Wellington CL. Namjoshi DR, et al. Among authors: martens km. Exp Neurol. 2017 Jun;292:80-91. doi: 10.1016/j.expneurol.2017.03.003. Epub 2017 Mar 6. Exp Neurol. 2017. PMID: 28274861 Free article.
ApoA-I deficiency increases cortical amyloid deposition, cerebral amyloid angiopathy, cortical and hippocampal astrogliosis, and amyloid-associated astrocyte reactivity in APP/PS1 mice.
Button EB, Boyce GK, Wilkinson A, Stukas S, Hayat A, Fan J, Wadsworth BJ, Robert J, Martens KM, Wellington CL. Button EB, et al. Among authors: martens km. Alzheimers Res Ther. 2019 May 13;11(1):44. doi: 10.1186/s13195-019-0497-9. Alzheimers Res Ther. 2019. PMID: 31084613 Free PMC article.
A Rational Structured Epitope Defines a Distinct Subclass of Toxic Amyloid-beta Oligomers.
Silverman JM, Gibbs E, Peng X, Martens KM, Balducci C, Wang J, Yousefi M, Cowan CM, Lamour G, Louadi S, Ban Y, Robert J, Stukas S, Forloni G, Hsiung GR, Plotkin SS, Wellington CL, Cashman NR. Silverman JM, et al. Among authors: martens km. ACS Chem Neurosci. 2018 Jul 18;9(7):1591-1606. doi: 10.1021/acschemneuro.7b00469. Epub 2018 Apr 16. ACS Chem Neurosci. 2018. PMID: 29614860
32 results