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Merging pathology with biomechanics using CHIMERA (Closed-Head Impact Model of Engineered Rotational Acceleration): a novel, surgery-free model of traumatic brain injury.
Namjoshi DR, Cheng WH, McInnes KA, Martens KM, Carr M, Wilkinson A, Fan J, Robert J, Hayat A, Cripton PA, Wellington CL. Namjoshi DR, et al. Among authors: cripton pa. Mol Neurodegener. 2014 Dec 1;9:55. doi: 10.1186/1750-1326-9-55. Mol Neurodegener. 2014. PMID: 25443413 Free PMC article.
A novel porcine model of traumatic thoracic spinal cord injury.
Lee JH, Jones CF, Okon EB, Anderson L, Tigchelaar S, Kooner P, Godbey T, Chua B, Gray G, Hildebrandt R, Cripton P, Tetzlaff W, Kwon BK. Lee JH, et al. J Neurotrauma. 2013 Feb 1;30(3):142-59. doi: 10.1089/neu.2012.2386. Epub 2013 Jan 14. J Neurotrauma. 2013. PMID: 23316955
Defining the biomechanical and biological threshold of murine mild traumatic brain injury using CHIMERA (Closed Head Impact Model of Engineered Rotational Acceleration).
Namjoshi DR, Cheng WH, Bashir A, Wilkinson A, Stukas S, Martens KM, Whyte T, Abebe ZA, McInnes KA, Cripton PA, Wellington CL. Namjoshi DR, et al. Among authors: cripton pa. Exp Neurol. 2017 Jun;292:80-91. doi: 10.1016/j.expneurol.2017.03.003. Epub 2017 Mar 6. Exp Neurol. 2017. PMID: 28274861 Free article.
CHIMERA repetitive mild traumatic brain injury induces chronic behavioural and neuropathological phenotypes in wild-type and APP/PS1 mice.
Cheng WH, Martens KM, Bashir A, Cheung H, Stukas S, Gibbs E, Namjoshi DR, Button EB, Wilkinson A, Barron CJ, Cashman NR, Cripton PA, Wellington CL. Cheng WH, et al. Among authors: cripton pa. Alzheimers Res Ther. 2019 Jan 12;11(1):6. doi: 10.1186/s13195-018-0461-0. Alzheimers Res Ther. 2019. PMID: 30636629 Free PMC article.
Repetitive closed-head impact model of engineered rotational acceleration (CHIMERA) injury in rats increases impulsivity, decreases dopaminergic innervation in the olfactory tubercle and generates white matter inflammation, tau phosphorylation and degeneration.
Vonder Haar C, Martens KM, Bashir A, McInnes KA, Cheng WH, Cheung H, Stukas S, Barron C, Ladner T, Welch KA, Cripton PA, Winstanley CA, Wellington CL. Vonder Haar C, et al. Among authors: cripton pa. Exp Neurol. 2019 Jul;317:87-99. doi: 10.1016/j.expneurol.2019.02.012. Epub 2019 Feb 26. Exp Neurol. 2019. PMID: 30822421
143 results