Rash LD - Search Results

1

Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy.

Simons C, Rash LD, Crawford J, Ma L, Cristofori-Armstrong B, Miller D, Ru K, Baillie GJ, Alanay Y, Jacquinet A, Debray FG, Verloes A, Shen J, Yesil G, Guler S, Yuksel A, Cleary JG, Grimmond SM, McGaughran J, King GF, Gabbett MT, Taft RJ. Simons C, et al. Among authors: rash ld. Nat Genet. 2015 Jan;47(1):73-7. doi: 10.1038/ng.3153. Epub 2014 Nov 24. Nat Genet. 2015. PMID: 25420144

2

Chemical synthesis and folding of APETx2, a potent and selective inhibitor of acid sensing ion channel 3.

Jensen JE, Durek T, Alewood PF, Adams DJ, King GF, Rash LD. Jensen JE, et al. Among authors: rash ld. Toxicon. 2009 Jul;54(1):56-61. doi: 10.1016/j.toxicon.2009.03.014. Epub 2009 Mar 21. Toxicon. 2009. PMID: 19306891

3

Venomics: a new paradigm for natural products-based drug discovery.

Vetter I, Davis JL, Rash LD, Anangi R, Mobli M, Alewood PF, Lewis RJ, King GF. Vetter I, et al. Among authors: rash ld. Amino Acids. 2011 Jan;40(1):15-28. doi: 10.1007/s00726-010-0516-4. Epub 2010 Feb 24. Amino Acids. 2011. PMID: 20177945 Review.

4

A dynamic pharmacophore drives the interaction between Psalmotoxin-1 and the putative drug target acid-sensing ion channel 1a.

Saez NJ, Mobli M, Bieri M, Chassagnon IR, Malde AK, Gamsjaeger R, Mark AE, Gooley PR, Rash LD, King GF. Saez NJ, et al. Among authors: rash ld. Mol Pharmacol. 2011 Nov;80(5):796-808. doi: 10.1124/mol.111.072207. Epub 2011 Aug 8. Mol Pharmacol. 2011. PMID: 21825095

5

Spider-venom peptides as therapeutics.

Saez NJ, Senff S, Jensen JE, Er SY, Herzig V, Rash LD, King GF. Saez NJ, et al. Among authors: rash ld. Toxins (Basel). 2010 Dec;2(12):2851-71. doi: 10.3390/toxins2122851. Epub 2010 Dec 20. Toxins (Basel). 2010. PMID: 22069579 Free PMC article. Review.

6

Cyclisation increases the stability of the sea anemone peptide APETx2 but decreases its activity at acid-sensing ion channel 3.

Jensen JE, Mobli M, Brust A, Alewood PF, King GF, Rash LD. Jensen JE, et al. Among authors: rash ld. Mar Drugs. 2012 Jul;10(7):1511-1527. doi: 10.3390/md10071511. Epub 2012 Jul 16. Mar Drugs. 2012. PMID: 22851922 Free PMC article.

7

Functional expression in Escherichia coli of the disulfide-rich sea anemone peptide APETx2, a potent blocker of acid-sensing ion channel 3.

Anangi R, Rash LD, Mobli M, King GF. Anangi R, et al. Among authors: rash ld. Mar Drugs. 2012 Jul;10(7):1605-1618. doi: 10.3390/md10071605. Epub 2012 Jul 23. Mar Drugs. 2012. PMID: 22851929 Free PMC article.

8

Production of recombinant disulfide-rich venom peptides for structural and functional analysis via expression in the periplasm of E. coli.

Klint JK, Senff S, Saez NJ, Seshadri R, Lau HY, Bende NS, Undheim EA, Rash LD, Mobli M, King GF. Klint JK, et al. Among authors: rash ld. PLoS One. 2013 May 7;8(5):e63865. doi: 10.1371/journal.pone.0063865. Print 2013. PLoS One. 2013. PMID: 23667680 Free PMC article.

9

Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2.

Schroeder CI, Rash LD, Vila-Farrés X, Rosengren KJ, Mobli M, King GF, Alewood PF, Craik DJ, Durek T. Schroeder CI, et al. Among authors: rash ld. Angew Chem Int Ed Engl. 2014 Jan 20;53(4):1017-20. doi: 10.1002/anie.201308898. Epub 2013 Dec 9. Angew Chem Int Ed Engl. 2014. PMID: 24323786

10

Isolation, synthesis and characterization of ω-TRTX-Cc1a, a novel tarantula venom peptide that selectively targets L-type Cav channels.

Klint JK, Berecki G, Durek T, Mobli M, Knapp O, King GF, Adams DJ, Alewood PF, Rash LD. Klint JK, et al. Among authors: rash ld. Biochem Pharmacol. 2014 May 15;89(2):276-86. doi: 10.1016/j.bcp.2014.02.008. Epub 2014 Feb 19. Biochem Pharmacol. 2014. PMID: 24561180

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