Harper JW - Search Results

1

Cyclin C is a haploinsufficient tumour suppressor.

Li N, Fassl A, Chick J, Inuzuka H, Li X, Mansour MR, Liu L, Wang H, King B, Shaik S, Gutierrez A, Ordureau A, Otto T, Kreslavsky T, Baitsch L, Bury L, Meyer CA, Ke N, Mulry KA, Kluk MJ, Roy M, Kim S, Zhang X, Geng Y, Zagozdzon A, Jenkinson S, Gale RE, Linch DC, Zhao JJ, Mullighan CG, Harper JW, Aster JC, Aifantis I, von Boehmer H, Gygi SP, Wei W, Look AT, Sicinski P. Li N, et al. Among authors: harper jw. Nat Cell Biol. 2014 Nov;16(11):1080-91. doi: 10.1038/ncb3046. Epub 2014 Oct 26. Nat Cell Biol. 2014. PMID: 25344755 Free PMC article.

2

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control.

Deng C, Zhang P, Harper JW, Elledge SJ, Leder P. Deng C, et al. Among authors: harper jw. Cell. 1995 Aug 25;82(4):675-84. doi: 10.1016/0092-8674(95)90039-x. Cell. 1995. PMID: 7664346 Free article.

3

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

Dulić V, Kaufmann WK, Wilson SJ, Tlsty TD, Lees E, Harper JW, Elledge SJ, Reed SI. Dulić V, et al. Among authors: harper jw. Cell. 1994 Mar 25;76(6):1013-23. doi: 10.1016/0092-8674(94)90379-4. Cell. 1994. PMID: 8137420

4

Retinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexes.

Adams PD, Li X, Sellers WR, Baker KB, Leng X, Harper JW, Taya Y, Kaelin WG Jr. Adams PD, et al. Among authors: harper jw. Mol Cell Biol. 1999 Feb;19(2):1068-80. doi: 10.1128/MCB.19.2.1068. Mol Cell Biol. 1999. PMID: 9891042 Free PMC article.

5

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase.

Koepp DM, Schaefer LK, Ye X, Keyomarsi K, Chu C, Harper JW, Elledge SJ. Koepp DM, et al. Among authors: harper jw. Science. 2001 Oct 5;294(5540):173-7. doi: 10.1126/science.1065203. Epub 2001 Aug 30. Science. 2001. PMID: 11533444

6

The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase.

Wei W, Jin J, Schlisio S, Harper JW, Kaelin WG Jr. Wei W, et al. Among authors: harper jw. Cancer Cell. 2005 Jul;8(1):25-33. doi: 10.1016/j.ccr.2005.06.005. Cancer Cell. 2005. PMID: 16023596 Free article.

7

A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling.

Draviam VM, Stegmeier F, Nalepa G, Sowa ME, Chen J, Liang A, Hannon GJ, Sorger PK, Harper JW, Elledge SJ. Draviam VM, et al. Among authors: harper jw. Nat Cell Biol. 2007 May;9(5):556-64. doi: 10.1038/ncb1569. Epub 2007 Apr 8. Nat Cell Biol. 2007. PMID: 17417629

8

The tumor suppressor CYLD regulates entry into mitosis.

Stegmeier F, Sowa ME, Nalepa G, Gygi SP, Harper JW, Elledge SJ. Stegmeier F, et al. Among authors: harper jw. Proc Natl Acad Sci U S A. 2007 May 22;104(21):8869-74. doi: 10.1073/pnas.0703268104. Epub 2007 May 10. Proc Natl Acad Sci U S A. 2007. PMID: 17495026 Free PMC article.

9

Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging.

Jin J, Li X, Gygi SP, Harper JW. Jin J, et al. Among authors: harper jw. Nature. 2007 Jun 28;447(7148):1135-8. doi: 10.1038/nature05902. Nature. 2007. PMID: 17597759

10

An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex.

Xu L, Sowa ME, Chen J, Li X, Gygi SP, Harper JW. Xu L, et al. Among authors: harper jw. Mol Biol Cell. 2008 Dec;19(12):5059-71. doi: 10.1091/mbc.e08-05-0473. Epub 2008 Sep 17. Mol Biol Cell. 2008. PMID: 18799622 Free PMC article.

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